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| Content Provider | Springer Nature Link |
|---|---|
| Author | Wang, Xiaona Meng, Xing Chu, Shunli Xiang, Xingchen Liu, Zhenzhen Zhao, Jinghui Zhou, Yanmin |
| Copyright Year | 2016 |
| Abstract | This study aimed to evaluate the effects of Ti–Nb–Zr–Ta–Si alloy implants on mineral apposition rate and new BIC contact in rabbits. Twelve Ti–Nb–Zr–Ta–Si alloy implants were fabricated and placed into the right femur sites in six rabbits, and commercially pure titanium implants were used as controls in the left femur. Tetracycline and alizarin red were administered 3 weeks and 1 week before euthanization, respectively. At 4 weeks and 8 weeks after implantation, animals were euthanized, respectively. Surface characterization and implant-bone contact surface analysis were performed by using a scanning electron microscope and an energy dispersive X-ray detector. Mineral apposition rate was evaluated using a confocal laser scanning microscope. Toluidine blue staining was performed on undecalcified sections for histology and histomorphology evaluation. Scanning electron microscope and histomorphology observation revealed a direct contact between implants and bone of all groups. After a healing period of 4 weeks, Ti–Nb–Zr–Ta–Si alloy implants showed significantly higher mineral apposition rate compared to commercially pure titanium implants (P < 0.05), whereas there was no significant difference between Ti–Nb–Zr–Ta–Si alloy implants and commercially pure titanium implants (P > 0.05) at 8 weeks. No significant difference of bone-to-implant contact was observed between Ti–Nb–Zr–Ta–Si alloy implants and commercially pure titanium implants implants after a healing period of 4 weeks and 8 weeks. This study showed that Ti–Nb–Zr–Ta–Si alloy implants could establish a close direct contact comparedto commercially pure titanium implants implants, improved mineral matrix apposition rate, and may someday be an alternative as a material for dental implants. |
| Starting Page | 1 |
| Ending Page | 10 |
| Page Count | 10 |
| File Format | |
| ISSN | 09574530 |
| Journal | Journal of Materials Science: Materials in Medicine |
| Volume Number | 27 |
| Issue Number | 9 |
| e-ISSN | 15734838 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2016-08-17 |
| Publisher Place | New York |
| Access Restriction | Subscribed |
| Subject Keyword | Biomaterials Biomedical Engineering Regenerative Medicine/Tissue Engineering Polymer Sciences Ceramics, Glass, Composites, Natural Materials Surfaces and Interfaces, Thin Films |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biomaterials Biophysics Bioengineering Biomedical Engineering |
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