NDLI: Cell adhesion on modified polyethylene

Content Provider	Springer Nature Link
Author	ŠvorčíK, V. Ročková, K. Dvořánková, B. Brož, L. Hnatowicz, V. Ochsner, R. Ryssel, H.
Copyright Year	2002
Abstract	Polyethylene (PE) was irradiated with 10 and 63 keV Ar$^{+}$ ions to fluences of 1 × 10$^{17}$ to 3 × 10$^{19}$ m$^{−2}$ and then it was grafted with aminoacid (alanine). The changes of surface polarity, electrical conductivity, and oxygen concentration were examined on pristine, as-irradiated, and irradiated-grafted PE. The in vitro adhesion of mice fibroblasts on the modified PE was evaluated 24 hours after inoculation. It was proved that for the PE irradiated at 10 keV ion energy, the presence of chemically bound alanine increases cell adhesion and its homogenity. For PE irradiated with 63 keV ions, however, the alanine grafting leads to a reduction of the number of adhering cells. It was found that a rising surface polarity increases cell adhesion, but when its value is too high the cell adhesion starts to decrease. No correlation between electrical conductivity and cell adhesion was observed. In general, higher cell adhesion is observed on modified PE in comparison with pristine one.
Starting Page	1183
Ending Page	1188
Page Count	6
File Format	PDF
ISSN	00222461
Journal	Journal of Materials Science
Volume Number	37
Issue Number	6
e-ISSN	15734803
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2002-01-01
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Polymer Sciences Industrial Chemistry/Chemical Engineering Characterization and Evaluation Materials Mechanics
Content Type	Text
Resource Type	Article
Subject	Ceramics and Composites Mechanics of Materials Mechanical Engineering Polymers and Plastics

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