NDLI: Inclusion Complexation of Carbaryl and β-Cyclodextrin in Solution and in the Solid State

Content Provider	Springer Nature Link
Author	Barbato, Francesco La Rotonda, Maria Immacolata Miro, Agnese Morrica, Patrizia Quaglia, Fabiana
Copyright Year	2000
Abstract	This study was carried out with the aim ofinvestigating the interactions betweenβ-cyclodextrin and carbaryl, a carbamatepesticide, and their effect on some physico-chemicalproperties of carbaryl, such as aqueous solubility andlipophilicity. The interactions between carbaryl andβ-cyclodextrin were thoroughly investigated bothin solution and in the solid state. The effect ofβ-cyclodextrin on the aqueous solubility ofcarbaryl was evaluated by the phase solubility method.The amount of carbaryl dissolved increased linearlywith the addition of β-cyclodextrin according toan A$_{L}$ type plot and without precipitation of thecomplex. The apparent stability constant of thecomplex was 289 ± 21 M$^{-1}$, assuming a 1 : 1stoichiometry; this value was confirmed by a methodbased on circular dichroism measurements.Equimolar carbaryl/β-cyclodextrin solid systemswere prepared by physical-mixing and freeze-drying,and fully characterised by Differential ScanningCalorimetry, X-ray powder diffractometry and FourierTransform Infra-Red analysis. The results of the solidstate study demonstrated that the freeze-drying methodyields a system with a high degree of amorphisationand yields an inclusion complex.The dissolution profile of the pesticide was affectedby the physico-chemical properties of each solidsystem, the freeze-dried form dissolving more rapidly. However, the physical association ofβ-cyclodextrin and carbaryl enhanced the aqueoussolubility of the insecticide as well.
Starting Page	423
Ending Page	433
Page Count	11
File Format	PDF
ISSN	09230750
Journal	Journal of Inclusion Phenomena and Macrocyclic Chemistry
Volume Number	38
Issue Number	1-4
e-ISSN	15731111
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2000-01-01
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Food Science Organic Chemistry Crystallography
Content Type	Text
Resource Type	Article
Subject	Chemistry Condensed Matter Physics Food Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Inclusion complexes of Sulconazole with β-cyclodextrin and hydroxypropyl β-cyclodextrin: characterization in aqueous solution and in solid state

Complexation of ebastine with β-cyclodextrin derivatives

Inclusion complexes of 5-flucytosine with β-cyclodextrin and hydroxypropyl-β-cyclodextrin: characterization in aqueous solution and in solid state

Large inclusion constants of β-cyclodextrin with carborane derivatives

A Solution and Solid State Study on 2-Hydroxypropyl-β-Cyclodextrin Complexation with Hyodeoxycholic Acid

The complexation of flurbiprofen with β-cyclodextrin: a NMR study in aqueous solution

Complexation of Fluvastatin Sodium with β-Cyclodextrin: NMR Spectroscopic Study in Solution

Solid-state NMR and wide-angle X-ray diffraction study of hydrofluoroether/β-cyclodextrin inclusion complex

The structure of inclusion complex of β-cyclodextrin with p-nitrophenoxyacetic acid in solution and the solid state

Inclusion Complexation of Carbaryl and β-Cyclodextrin in Solution and in the Solid State

Similar Documents

Inclusion complexes of Sulconazole with β-cyclodextrin and hydroxypropyl β-cyclodextrin: characterization in aqueous solution and in solid state

Complexation of ebastine with β-cyclodextrin derivatives

Inclusion complexes of 5-flucytosine with β-cyclodextrin and hydroxypropyl-β-cyclodextrin: characterization in aqueous solution and in solid state

Large inclusion constants of β-cyclodextrin with carborane derivatives

A Solution and Solid State Study on 2-Hydroxypropyl-β-Cyclodextrin Complexation with Hyodeoxycholic Acid

The complexation of flurbiprofen with β-cyclodextrin: a NMR study in aqueous solution

Complexation of Fluvastatin Sodium with β-Cyclodextrin: NMR Spectroscopic Study in Solution

Solid-state NMR and wide-angle X-ray diffraction study of hydrofluoroether/β-cyclodextrin inclusion complex

The structure of inclusion complex of β-cyclodextrin with p-nitrophenoxyacetic acid in solution and the solid state

Inclusion Complexation of Carbaryl and β-Cyclodextrin in Solution and in the Solid State