NDLI: HAT transposable elements and their derivatives: an analysis in the 12 Drosophila genomes

Content Provider	Springer Nature Link
Author	Freitas Ortiz, Mauro Lorenzatto, Karina Rodrigues Corrêa, Bruna Renata Silva Loreto, Elgion Lucio Silva
Copyright Year	2010
Abstract	Transposable elements (TEs) comprise a significant fraction of the genome, and some models of the TE “life cycle” suggest that, in the last phases of the cycle, TEs should be represented, in the genomes, by inactive and degenerated copies. In this study, we analyzed, using a bioinformatics approach, the autonomous hAT elements and their derivatives (active non-autonomous, MITE relatives and degenerated copies) in 12 Drosophila genomes. We found 28 hAT elements that had derivatives. Most copies had features that suggested that they were active, while only a few degenerated copies were found. Because hAT elements comprise an evolutionarily old superfamily, one should expect to find many degenerated copies within the genome, although this was not observed in our study. These results suggest that primarily active copies of hAT elements are maintained in the euchromatic regions of the genome and that degenerated copies are removed from the genome by natural selection.
Starting Page	649
Ending Page	655
Page Count	7
File Format	PDF
ISSN	00166707
Journal	Genetica
Volume Number	138
Issue Number	6
e-ISSN	15736857
Language	English
Publisher	Springer Netherlands
Publisher Date	2010-02-04
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Transposable element Non-autonomous elements MITEs Target site duplication Microbial Genetics and Genomics Human Genetics Plant Genetics & Genomics Animal Genetics and Genomics Life Sciences
Content Type	Text
Resource Type	Article
Subject	Genetics Plant Science Medicine Animal Science and Zoology Insect Science

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