NDLI: Cytogenetic mapping of immunoglobulin heavy chain genes in Antarctic fish

Content Provider	Springer Nature Link
Author	Pisa, Eva Coscia, Maria Rosaria Mazzei, Federico Ghigliotti, Laura Coutanceau, Jean Pierre Ozouf Costaz, Catherine Oreste, Umberto
Copyright Year	2006
Abstract	The chromosomal location of the IgH locus has been analyzed in several bony fish of the Antarctic perciform group Notothenioidei. Two IgH probes were prepared from the species Trematomus bernacchii (family Nototheniidae, tribe Trematominae) and mapped onto the chromosomes of ten species belonging to the same genus (Trematomus) and in two outgroups, through one-color and two-color FISH. A single location of the IgH locus was found in the majority of the species examined, including the outgroups, whereas in four of them the IgH genes splited to two chromosomal loci. RT-PCR experiments revealed the presence of three allelic sequences in T. newnesi, a species in which the IgH genes were organized in two chromosomal loci. Possible pathways leading to IgH genes duplication during the diversification of trematomine fishes were inferred from the analysis of the FISH patterns in a phylogenetic context. The present work provides the first comprehensive picture of IgH genes organization at chromosomal level in a bony fish group.
Starting Page	9
Ending Page	17
Page Count	9
File Format	PDF
ISSN	00166707
Journal	Genetica
Volume Number	130
Issue Number	1
e-ISSN	15736857
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2006-08-15
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Antarctic fish Chromosomes FISH Cytogenetic mapping IgH locus Trematomus Microbial Genetics and Genomics Human Genetics Plant Genetics & Genomics Animal Genetics and Genomics Life Sciences
Content Type	Text
Resource Type	Article
Subject	Genetics Plant Science Medicine Animal Science and Zoology Insect Science

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