NDLI: The effect of praziquantel applied per os on selected haematological and biochemical indices in common carp (Cyprinus carpio L.)

Content Provider	Springer Nature Link
Author	Sudová, Eliška Piačková, Veronika Kroupová, Hana Pijáček, Martin Svobodová, Zdeňka
Copyright Year	2008
Abstract	The aim of the study was to assess the effects of the anthelminthic, praziquantel, on the haematological and biochemical indices of the blood of common carp (Cyprinus carpio L.). Fish were divided into six groups: two groups received 30 mg kg−1 body weight (bw) of praziquantel, and two groups were given 50 mg kg−1 bw of praziquantel mixed into the heat-treated amyloid vehicle. Fish in the remaining two groups were given only the amyloid vehicle and were used as controls. Fish were examined either 24 or 96 h after administration. Praziquantel treatment was characterised by a significantly lower erythrocyte count, haemoglobin level, packed cell volume and total protein at both dose levels after 24 h compared with the controls, but these parameters were similar to the control values at 96 h. The activity of alanine aminotransferase (ALT) was significantly higher after 96 h in the treated groups, which could be attributed to slight hepatocyte damage caused by praziquantel. However, the differences between the treated and the control groups were not great, and we presumed that they were reversible.
Starting Page	599
Ending Page	605
Page Count	7
File Format	PDF
ISSN	09201742
Journal	Fish Physiology and Biochemistry
Volume Number	35
Issue Number	4
e-ISSN	15735168
Language	English
Publisher	Springer Netherlands
Publisher Date	2008-11-25
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Biochemistry Carp Treatment Anthelminthic Zoology Animal Biochemistry Animal Anatomy / Morphology / Histology Animal Physiology Freshwater & Marine Ecology
Content Type	Text
Resource Type	Article
Subject	Physiology Medicine Biochemistry Aquatic Science

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