NDLI: Trends in colorectal cancer incidence and mortality in the Israeli Jewish ethnic populations

Please wait, while we are loading the content...

Trends in colorectal cancer incidence and mortality in the Israeli Jewish ethnic populations

Content Provider	Springer Nature Link
Author	Barchana, Micha Liphshitz, Irena Rozen, Paul
Copyright Year	2004
Abstract	Background: Ashkenazi Jews, as compared to non-European Jews and non-Jews, are at increased risk for colorectal cancer (CRC), this is attributed to genetic susceptibility and/or lifestyle. Aims: To follow Israeli long-term trends in CRC incidence and mortality and their associations with ethnicity. Methods: All Israeli CRC data accumulated 1970–2001 was used, age standardized rates (adjusted to world standard population) was computed by cancer site, US Surveillance, Epidemiology and End Results Program (SEER) Stage and ethnic group (continent of birth: Europe–America, Asia, Africa, Israel). Results: From 1970, CRC incidence increased 190% in males and 140% in females; mainly colon cancer (270% and 185% respectively) (P < 0.01), while rectal cancer incidence decreased and is now stable. Stage 3 CRC increased while stage 4 decreased significantly (P < 0.01 for both). In 2001, CRC incidence per 100,000 in European–American-born males was 48.3, Asian and African born 35.5 and Israeli born 32.7 (relative risk (RR) 1.36, P=0.03), while European–American female rates were 35 and all the others 26 (RR 1.35, P < 0.01). Overall survival increased 9% over 30 years (P 0.01), 5 years survival since 1988–1996 for European–American born was 43.1%, Asian 46.7%, African 47.5% and Israeli 55.8%. Stage-2 CRC 5 years survivals for 1970–1996 (most had no post surgical treatment) for European–American born were 41.7%, Asian and African 44.8% and Israeli 53.4% (P < 0.05). Stage-3 CRC survivals (most received adjuvant therapy in addition to surgery) for European–American born was 38.8%, Asian and African 43.3% and Israeli 45.1% (P < 0.01). Conclusions: Colon cancer has increased in Israel, mainly in males and European–American born. Israeli-born Jews (of 20 to 60% mixed ethnicity and lifestyle habits) have the lowest incidence and best survival data for stages-2 and -3 CRC. There is evidence of ethnic survival advantage and possibly in response to adjuvant oncological therapy.
Starting Page	207
Ending Page	214
Page Count	8
File Format	PDF
ISSN	13899600
Journal	Familial Cancer
Volume Number	3
Issue Number	3-4
e-ISSN	15737292
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2004-01-01
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Human Genetics Oncology Epidemiology Counselling
Content Type	Text
Resource Type	Article
Subject	Genetics Cancer Research Genetics (clinical) Oncology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

The Jewish people: their ethnic history, genetic disorders and specific cancer susceptibility

Peritoneal carcinoma in women with genetic susceptibility: implications for Jewish populations

Ashkenazi Jewish genetic disorders

Determinants of Preferences for Genetic Counselling in Jewish Women

Mutation spectrum in HNPCC in the Israeli population

History of the International Collaborative Group on Hereditary NonPolyposis Colorectal Cancer

Referrals of patients to colorectal cancer genetics services in south-east Scotland

Inflammatory bowel disease in Ashkenazi Jews: implications for familial colorectal cancer

Prognosis in DNA Mismatch Repair Deficient Colorectal Cancer: are all MSI Tumours Equivalent?

Trends in colorectal cancer incidence and mortality in the Israeli Jewish ethnic populations

Similar Documents

The Jewish people: their ethnic history, genetic disorders and specific cancer susceptibility

Peritoneal carcinoma in women with genetic susceptibility: implications for Jewish populations

Ashkenazi Jewish genetic disorders

Determinants of Preferences for Genetic Counselling in Jewish Women

Mutation spectrum in HNPCC in the Israeli population

History of the International Collaborative Group on Hereditary NonPolyposis Colorectal Cancer

Referrals of patients to colorectal cancer genetics services in south-east Scotland

Inflammatory bowel disease in Ashkenazi Jews: implications for familial colorectal cancer

Prognosis in DNA Mismatch Repair Deficient Colorectal Cancer: are all MSI Tumours Equivalent?

Trends in colorectal cancer incidence and mortality in the Israeli Jewish ethnic populations