NDLI: Familial gastric cancer: guidelines for diagnosis, treatment and periodic surveillance

Content Provider	Springer Nature Link
Author	Kluijt, Irma Sijmons, Rolf H. Hoogerbrugge, Nicoline Plukker, John T. Jong, Daphne Krieken, J. Han Hillegersberg, Richard Ligtenberg, Marjolijn Bleiker, Eveline Cats, Anemieke
Copyright Year	2012
Abstract	Hereditary diffuse gastric cancer (HDGC) is a relatively rare disorder, with a mutated CDH1 gene as the only known cause. Carriers of a germline mutation in CDH1 have a lifetime risk of >80% of developing diffuse gastric cancer. As periodic gastric surveillance is of limited value in detecting early stages of HDGC, prophylactic gastrectomy is advised for this patient group. Little is known about other types of familial gastric cancer. The Dutch working group on hereditary gastric cancer has formulated guidelines for various aspects of medical management for families and individuals at high risk of developing gastric cancer, including criteria for referral, classification, diagnostics, and periodic gastric surveillance. These guidelines are not limited to HDGC and are therefore partially complementary to the guidelines on hereditary diffuse gastric cancer of the international gastric cancer linkage consortium (IGCLC 2010). In order to optimize the care and increase the knowledge on hereditary gastric cancer it is important to centralize medical care for these patients. National and international collaboration is warranted to improve the quality of research by increasing the size of study cohorts.
Starting Page	363
Ending Page	369
Page Count	7
File Format	PDF
ISSN	13899600
Journal	Familial Cancer
Volume Number	11
Issue Number	3
e-ISSN	15737292
Language	English
Publisher	Springer Netherlands
Publisher Date	2012-03-03
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Familial gastric cancer Hereditary diffuse gastric cancer CDH1 Gastric surveillance Prophylactic gastrectomy Intestinal gastric cancer Epidemiology Biomedicine general Human Genetics Cancer Research
Content Type	Text
Resource Type	Article
Subject	Genetics Cancer Research Genetics (clinical) Oncology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

An investigation of the factors effecting high-risk individuals’ decision-making about prophylactic total gastrectomy and surveillance for hereditary diffuse gastric cancer (HDGC)

Hereditary diffuse gastric cancer: association with lobular breast cancer

Prophylactic total gastrectomy in hereditary diffuse gastric cancer: identification of two novel CDH1 gene mutations—a clinical observational study

Hereditary Diffuse Gastric Cancer—Update Based on the Current Consort Recommendations

CDH1 gene mutations do not contribute in hereditary diffuse gastric cancer in Poland

Prophylactic Gastrectomy in Familial Gastric Cancer: Case Report and Review of Literature

The identification and management of hereditary diffuse gastric cancer in a large Jordanian family

Hereditary diffuse gastric cancer: association with lobular breast cancer

Searching for E-cadherin gene mutations in early onset diffuse gastric cancer and hereditary diffuse gastric cancer in Korean patients

Familial gastric cancer: guidelines for diagnosis, treatment and periodic surveillance

Similar Documents

An investigation of the factors effecting high-risk individuals’ decision-making about prophylactic total gastrectomy and surveillance for hereditary diffuse gastric cancer (HDGC)

Hereditary diffuse gastric cancer: association with lobular breast cancer

Prophylactic total gastrectomy in hereditary diffuse gastric cancer: identification of two novel CDH1 gene mutations—a clinical observational study

Hereditary Diffuse Gastric Cancer—Update Based on the Current Consort Recommendations

CDH1 gene mutations do not contribute in hereditary diffuse gastric cancer in Poland

Prophylactic Gastrectomy in Familial Gastric Cancer: Case Report and Review of Literature

The identification and management of hereditary diffuse gastric cancer in a large Jordanian family

Hereditary diffuse gastric cancer: association with lobular breast cancer

Searching for E-cadherin gene mutations in early onset diffuse gastric cancer and hereditary diffuse gastric cancer in Korean patients

Familial gastric cancer: guidelines for diagnosis, treatment and periodic surveillance