NDLI: Investigation of the effects of static magnetic field on apoptosis in bone marrow stem cells of rat

Content Provider	Springer Nature Link
Author	Tavasoli, Zeinab Abdolmaleki, Parviz Mowla, Seyed Javad Ghanati, Faezeh Sarvestani, Amir Sabet
Copyright Year	2009
Abstract	This research was carried out to evaluate the influence of static magnetic field on the rate of apoptosis in bone marrow stem cells (BMSCs) of rats. Extracted cells were suspended in αMEM as a culture media for 48 h. After that, cells were exposed to 15 mT static magnetic field (SMF) for 5 h, incessantly with or without FeCl2. The rate of apoptosis was then assessed via flow cytometery. The results showed that either treatment with FeCl2 or exposure to SMF enhanced the rate of apoptotic cells. Moreover, cells that were treated simultaneously with FeCl2 and SMF have higher rate of apoptosis. An increase in apoptosis by 26.5% was induced by SMF alone and an increase in apoptosis by 28.2% was induced by a combination of FeCl2 and SMF, compared to their corresponding controls. The results recommended that the effects of SMF on apoptosis may be related to increment of the number of free radicals in the cells.
Starting Page	220
Ending Page	224
Page Count	5
File Format	PDF
ISSN	02511088
Journal	Environmentalist
Volume Number	29
Issue Number	2
e-ISSN	15732991
Language	English
Publisher	Springer US
Publisher Date	2009-02-11
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Stem cell Apoptosis Static magnetic field FeCl2 Flow cytometry Environmental Management Economic Geology Ecology Nature Conservation
Content Type	Text
Resource Type	Article
Subject	Environmental Science

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