NDLI: Preliminary occurrence studies of antibiotic residues in Hong Kong and Pearl River Delta

Content Provider	Springer Nature Link
Author	Chen, YuMei Leung, Kelvin Sze Yin Wong, Jonathan Woon Chung Selvam, Ammaiyappan
Copyright Year	2012
Abstract	An improved liquid chromatography–tandem mass spectrometry (LC-MS/MS) method was developed and validated to investigate the occurrence of selected antibiotic residues in Hong Kong and Pearl River Delta. LC and MS parameters were optimized to produce the maximum analytical responses for each compound. The established method targeted five groups of antibiotics, namely, macrolides, sulfonamides, tetracyclines, quinolones, and amphenicols. The method was validated for three types of environmental water matrices, namely, reservoir, river, and estuarine waters. Low detection limits of 0.17–0.18 ng/L for macrolides, 0.22–0.34 ng/L for quinolones, 0.67–1.65 ng/L for tetracyclines, and 0.27–0.56 ng/L for sulfonamides were obtained. No apparent interferences were observed in the chromatograms of all antibiotics groups. The developed method was preliminarily used to analyze water samples collected from Yuen Long River in New Territories, Hong Kong and four sites along the Pearl River Delta. Results showed that high level of tetracycline was found among the groups tested in the local river samples. In Pearl River Delta, we identified significant levels of erythromycin, roxithromycin, and sulfadiazine in Shenzhen Reservoir.
Starting Page	745
Ending Page	754
Page Count	10
File Format	PDF
ISSN	01676369
Journal	Environmental Monitoring and Assessment
Volume Number	185
Issue Number	1
e-ISSN	15732959
Language	English
Publisher	Springer Netherlands
Publisher Date	2012-03-07
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Liquid chromatography–tandem mass spectrometry Method validation Antibiotics in environment Environmental Monitoring/Analysis Environmental Management Ecotoxicology Atmospheric Protection/Air Quality Control/Air Pollution Ecology
Content Type	Text
Resource Type	Article
Subject	Pollution Medicine Management, Monitoring, Policy and Law

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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