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| Content Provider | Springer Nature Link |
|---|---|
| Author | Torres, Nádia Hortense Aguiar, Mario Mamede Ferreira, Luiz Fernando Romanholo Américo, Juliana Heloisa Pinê Machado, Ângela Maria Cavalcanti, Eliane Bezerra Tornisielo, Valdemar Luiz |
| Copyright Year | 2015 |
| Abstract | The growing use of pharmaceutical drug is mainly due to several diseases in human and in animal husbandry. As these drugs are discharged into waterways via wastewater, they cause a major impact on the environment. Many of these drugs are hormones; in which even at low concentrations can alter metabolic and physiological functions in many organisms. Hormones were found in surface water, groundwater, soil, and sediment at concentrations from nanograms to milligrams per liter of volume—quantities known to cause changes in the endocrine system of aquatic organisms. This study aimed to develop a methodology for hormone detection (estriol, estrone, 17β-estradiol, 17α-ethinylestradiol, progesterone, and testosterone) on surface and treated water samples. Sample toxicity was assessed by ecotoxicology tests using Daphnia magna. A liquid chromatograph coupled to a mass spectrometer with an electrospray ionization source (LC-ESI-MS/MS) was used for the analysis. The results showed that samples were contaminated by the hormones estriol, estrone, progesterone, 17β-estradiol, and 17α-ethinylestradiol during the sampling period, and the highest concentrations measured were 90, 28, 26, 137, and 194 ng·L−1, respectively. This indicates the inflow of sewage containing these hormones at some points in the Piracicaba River in the State of Sao Paulo—Brazil. Results indicated little toxicity of the hormone estriol in D. magna, indicating that chronic studies with this microcrustacean are necessary. |
| Starting Page | 1 |
| Ending Page | 13 |
| Page Count | 13 |
| File Format | |
| ISSN | 01676369 |
| Journal | Environmental Monitoring and Assessment |
| Volume Number | 187 |
| Issue Number | 6 |
| e-ISSN | 15732959 |
| Language | English |
| Publisher | Springer International Publishing |
| Publisher Date | 2015-05-28 |
| Publisher Place | Cham |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Surface water Liquid chromatography Hormones Mass spectrometer Environmental contamination Aquatic environment Environmental Monitoring/Analysis Environmental Management Ecotoxicology Atmospheric Protection/Air Quality Control/Air Pollution Ecology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pollution Medicine Management, Monitoring, Policy and Law |
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