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| Content Provider | Springer Nature Link |
|---|---|
| Author | Dharma wardana, M. W. C. Amarasiri, Sarath L. Dharmawardene, Nande Panabokke, C. R. |
| Copyright Year | 2014 |
| Abstract | High incidence of chronic kidney disease of unknown aetiology (CKDU) in Sri Lanka is shown to correlate with the presence of irrigation works and rivers that bring-in ‘nonpoint source’ fertilizer runoff from intensely agricultural regions. We review previous attempts to link CKDU with As, Cd and other standard toxins. Those studies (e.g. the WHO-sponsored study), while providing a wealth of data, are inconclusive in regard to aetiology. Here, we present new proposals based on increased ionicity of drinking water due to fertilizer runoff into the river system, redox processes in the soil and features of ‘tank’-cascades and aquifers. The consequent chronic exposure to high ionicity in drinking water is proposed to debilitate the kidney via a Hofmeister-type (i.e. protein-denaturing) mechanism. |
| Starting Page | 221 |
| Ending Page | 231 |
| Page Count | 11 |
| File Format | |
| ISSN | 02694042 |
| Journal | Environmental Geochemistry and Health |
| Volume Number | 37 |
| Issue Number | 2 |
| e-ISSN | 15732983 |
| Language | English |
| Publisher | Springer Netherlands |
| Publisher Date | 2014-08-14 |
| Publisher Place | Dordrecht |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Kidney disease Water quality Electrolytes Protein denaturing Fertilizers Soils Aquifers Sri Lanka Environmental Health Geochemistry Terrestrial Pollution Soil Science & Conservation Environmental Chemistry Public Health |
| Content Type | Text |
| Resource Type | Article |
| Subject | Environmental Chemistry Medicine Geochemistry and Petrology Environmental Engineering Water Science and Technology |
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