NDLI: Serum biochemical analysis to indicate pathogenic risk on mouse Mus musculus exposure to source of drinking water

Content Provider	Springer Nature Link
Author	Yun, Shi Feng Tian, Xiao Yun Cheng, Shu Pei Zhang, Yan Li, Ai Min Zhang, Li Bo Zhang, Xu Xiang Chen, Li Wu, Bing Guo, Lian Qin Shi, Yun Zhong
Copyright Year	2011
Abstract	The 18 biochemical parameters of serum were measured to analyze the pathogenic risks of the Yangtze River Source of Drinking Water in Nanjing area (YZR-SDW-NJ) on mouse Mus musculus for protection of human health in this research. The male mice Mus musculus were sampled and fed with YZR-SDW-NJ for 90 days then the eighteen serum biochemical levels were measured with Automatic Biochemical Analysis/RerLi 600. And the parameter data were treated by One-Way ANOVA statistic approach. The results showed that five parameter levels for the sample group mice were different from those for the control group significantly (0.01 < P or 0.05 < P). Four 4 of the 5 altered parameter levels were decreased including glutamate pyruvate transaminase 38% lower, glutamine-oxaloacetic transaminase 24% lower, triglyceride 76% lower and cystatin C 73% lower, only creatinine level was 26% higher than that in the control group. The data suggest that YZR-SDW-NJ had toxicity on the mouse and the organic pollutants in YZR-SDW-NJ might lead to liver, kidney, cardiovascular and metabolic pathogenic risks on the human beings. The results might be cited as evidence to control pollutants in the source water for the protection of NJ people’s health.
Starting Page	1078
Ending Page	1082
Page Count	5
File Format	PDF
ISSN	09639292
Journal	Ecotoxicology
Volume Number	20
Issue Number	5
e-ISSN	15733017
Language	English
Publisher	Springer US
Publisher Date	2011-04-09
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Yangtze River Mus musculus Serum parameter Biochemical analysis Pathogenic risk Environmental Management Ecotoxicology Environment Ecology
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Medicine Toxicology Management, Monitoring, Policy and Law

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