NDLI: IntelliGEN: A Distributed Workflow System for Discovering Protein-Protein Interactions

Content Provider	Springer Nature Link
Author	Kochut, Krys Arld, Jonathan Sheth, Amit Miller, John Kraemer, Eileen Arpinar, Budak Cardoso, Jorge
Copyright Year	2003
Abstract	A large genomics project involves a significant number of researchers and technicians performing dozens of tasks, either manual (e.g. performing laboratory experiments), computer assisted (e.g. looking for genes in the GENBANK database), or sometimes performed entirely automatically by the computer (e.g. sequence assembly). It has become apparent that managing such projects poses overwhelming problems and may lead to results of lower or even unacceptable quality, or possibly drastically increased project costs. In this paper, we present a design and an initial implementation of a distributed workflow system created to schedule and support activities in a genomics laboratory. The focus of the activities in the laboratory is the discovery of protein-protein interactions of fungi, specifically Neurospora crassa. We present our approach of developing, adapting and applying workflow technology in the genomics lab and illustrate it using one distinct part of a larger workflow to discover protein-protein interactions. Novel features of our system include the ability to monitor the quality and timeliness of the results and if necessary, suggesting and incorporating changes to the selected tasks and their scheduling.
Starting Page	43
Ending Page	72
Page Count	30
File Format	PDF
ISSN	09268782
Journal	Distributed and Parallel Databases
Volume Number	13
Issue Number	1
e-ISSN	15737578
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2003-01-01
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Processor Architectures Computer Communication Networks Data Structures, Cryptology and Information Theory Information Storage and Retrieval
Content Type	Text
Resource Type	Article
Subject	Information Systems and Management Information Systems Software Hardware and Architecture

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
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IntelliGEN: A Distributed Workflow System for Discovering Protein-Protein Interactions