NDLI: The very long telomeres in Sorex granarius (Soricidae, Eulipothyphla) contain ribosomal DNA

Content Provider	Springer Nature Link
Author	Zhdava, Natalia S. Minina, Julia M. Karamisheva, Tatjana V. Draskovic, Irena Rubtsov, Nikolai B. Londoño Vallejo, Jose Arturo
Copyright Year	2007
Abstract	Two closely related shrew species, Sorex granarius and Sorex araneus, in which Robertsonian rearrangements have played a primary role in karyotype evolution, present very distinct telomere length patterns. S. granarius displays hyperlong telomeres specifically associated with the short arms of acrocentrics, whereas telomere lengths in S. araneus are rather short and homogenous. Using a combined approach of chromosome and fibre FISH, modified Q-FISH, 3D-FISH, Ag-NOR staining and TRF analysis, we carried out a comparative analysis of telomeric repeats and rDNA distribution on chromosome ends of Sorex granarius. Our results show that rDNA sequences forming active nuclear organizing regions are interspersed with the long telomere tracts of all short arms of acrocentrics. These observations suggest that the major rearrangements that gave rise to today’s karyotype in S. granarius were accompanied by a profound reorganization of chromosome ends, which comprised extensive amplification of telomeric and rDNA repeats on the short arms of acrocentrics and finally contributed to the stabilization of telomeres. This is the first time that such telomeric structures have been observed in any mammalian species.
Starting Page	881
Ending Page	890
Page Count	10
File Format	PDF
ISSN	09673849
Journal	Chromosome Research
Volume Number	15
Issue Number	7
e-ISSN	15736849
Language	English
Publisher	Springer Netherlands
Publisher Date	2007-10-01
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	chromosome evolution rDNA shrew Sorex telomere Cell Biology Human Genetics Animal Genetics and Genomics Plant Genetics & Genomics
Content Type	Text
Resource Type	Article
Subject	Genetics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Unusual distribution pattern of telomeric repeats in the shrews Sorex araneus and Sorex granarius

Telomeres in evolution and evolution of telomeres

Two retrotransposons maintain telomeres in Drosophila

The localization of ribosomal DNA in Sciaridae (Diptera: Nematocera) reassessed

Ribosomal DNA locus evolution in Nemesia: transposition rather than structural rearrangement as the key mechanism?

Whole-arm reciprocal translocation in a hybrid population of Sorex araneus

Complex rearrangements are involved in Cephalanthera (Orchidaceae) chromosome evolution

Three-dimensional organization of interphase fibroblast nuclei in two closely related shrew species (Sorex granarius and Sorex araneus) differing in the structures of their chromosome termini

Telomere maintenance, function and evolution: the yeast paradigm

The very long telomeres in Sorex granarius (Soricidae, Eulipothyphla) contain ribosomal DNA

Similar Documents

Unusual distribution pattern of telomeric repeats in the shrews Sorex araneus and Sorex granarius

Telomeres in evolution and evolution of telomeres

Two retrotransposons maintain telomeres in Drosophila

The localization of ribosomal DNA in Sciaridae (Diptera: Nematocera) reassessed

Ribosomal DNA locus evolution in Nemesia: transposition rather than structural rearrangement as the key mechanism?

Whole-arm reciprocal translocation in a hybrid population of Sorex araneus

Complex rearrangements are involved in Cephalanthera (Orchidaceae) chromosome evolution

Three-dimensional organization of interphase fibroblast nuclei in two closely related shrew species (Sorex granarius and Sorex araneus) differing in the structures of their chromosome termini

Telomere maintenance, function and evolution: the yeast paradigm

The very long telomeres in Sorex granarius (Soricidae, Eulipothyphla) contain ribosomal DNA