NDLI: Alcohol and risk of breast cancer in Mexican women

Content Provider	Springer Nature Link
Author	Beasley, Jeannette M. Coronado, Gloria D. Livaudais, Jennifer Angeles Llerenas, Angélica Ortega Olvera, Carolina Romieu, Isabelle Lazca Ponce, Eduardo Torres Mejía, Gabriela
Copyright Year	2010
Abstract	Little is known about the relationship between alcohol intake and breast cancer risk among Mexican women. This association may be modified by folate and Vitamin B12.A population-based case–control study conducted in Mexico recruited 1,000 incident breast cancer cases aged 35–69 and 1,074 controls matched on age, region, and health care system. In-person interviews were conducted to assess breast cancer risk factors and recent diet using a food frequency questionnaire. Conditional logistic regression models estimated adjusted odds ratios and 95% confidence intervals.Over one-half (57%) of cases and less than one-half of controls (45%) reported any lifetime alcohol consumption. Compared with never drinkers, women reporting ever drinking (Adjusted OR = 1.25, 95% CI = 0.99–1.58) had a greater odds of breast cancer. There was evidence for interaction in the association between ever consuming any alcohol and breast cancer by folate (p for interaction = 0.04) suggesting women with lower folate intake had a higher odds of breast cancer (Adjusted OR = 1.99, 95% CI = 1.26–3.16) compared to women with higher folate intake (OR = 1.12, 95% CI = 0.69–1.83).Our findings support evidence that any alcohol intake increases risk of breast cancer. Insufficient intake of folate may further elevate risk for developing breast cancer among women who consume alcohol.
Starting Page	863
Ending Page	870
Page Count	8
File Format	PDF
ISSN	09575243
Journal	Cancer Causes & Control
Volume Number	21
Issue Number	6
e-ISSN	15737225
Language	English
Publisher	Springer Netherlands
Publisher Date	2010-02-13
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Breast cancer Alcohol consumption Folate and vitamin B12 Mexican women Hispanic Hematology Epidemiology Public Health/Gesundheitswesen Oncology Biomedicine general Cancer Research
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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