NDLI: Consumption of soy foods and the risk of breast cancer: findings from the Japan Collaborative Cohort (JACC) Study

Content Provider	Springer Nature Link
Author	Nishio, Kazuko Niwa, Yoshimitsu Toyoshima, Hideaki Tamakoshi, Koji Kondo, Takaaki Yatsuya, Hiroshi Yamamoto, Akio Suzuki, Sadao Tokudome, Shinkan Lin, Yingsong Wakai, Kenji Hamajima, buyuki Tamakoshi, Akiko
Copyright Year	2007
Abstract	The association between a lower incidence of breast cancer within the Asian population and the consumption of a diet high in soy has recently been the subject of much attention. To examine whether soy foods really have protective effects against breast cancer and how their influence on breast cancer is modified according to menopausal status, we conducted a population-based, prospective cohort study in Japan.We analyzed the data from the Japan Collaborative Cohort (JACC) Study. From 1988 to 1990, 30,454 women aged 40–79 years, completed a questionnaire on diet and other lifestyle features. Hazard ratios (HRs) were computed to examine the association between soy intake and the risk of breast cancer.During the mean follow-up of 7.6 years, 145 cases of breast cancer were documented. We found no significant association between the risk of breast cancer and consumption of tofu, boiled beans, and miso soup; the multivariate HRs (95% CI) in the highest category of consumption were 1.14 (0.74–1.77), 0.77 (0.47–1.27) and 1.01 (0.65–1.56), respectively. Only among postmenopausal women, we found no significant associations between soy foods and the risk of breast cancer.This prospective study suggests that consumption of soy food has no protective effects against breast cancer. Further large-scale investigations eliciting genetic factors may clarify different roles of various soybean-ingredient foods on the risk of breast cancer.
Starting Page	801
Ending Page	808
Page Count	8
File Format	PDF
ISSN	09575243
Journal	Cancer Causes & Control
Volume Number	18
Issue Number	8
e-ISSN	15737225
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2007-07-06
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Breast cancer Breast neoplasms Soy Soy foods Cohort study Cohort studies Hematology Epidemiology Public Health/Gesundheitswesen Oncology Biomedicine general Cancer Research
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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