NDLI: Vegetable and fruit consumption and lung cancer risk in the Netherlands Cohort Study on Diet and Cancer

Content Provider	Springer Nature Link
Author	Voorrips, Laura E. Goldbohm, R. Alexandra Verhoeven, Dorette T.H. van Poppel, Geert A.F.C. Sturmans, Ferd Hermus, Rudolph J.J. van den Brandt, Piet A.
Copyright Year	2000
Abstract	Objective: The purpose was to study the association between vegetable and fruit consumption and lung cancer incidence using 1074 cases after 6.3 years of follow-up in the Netherlands Cohort Study. Methods: Dietary intake was assessed using a 150-item food-frequency questionnaire. Multivariate models were used including age, sex, family history of lung cancer, highest educational level attained, and smoking history. Results: Statistically significant inverse associations were found with total vegetables and most vegetable groups. Rate ratios (RRs) based on consumption frequency showed the strongest effect of vegetables from the Brassica group (RR 0.5, 95% confidence interval (95% CI) 0.3–0.9, for consumption ≥3 times per week versus ≤ once a month). RR of highest versus lowest quintile of total vegetable consumption was 0.7 (95% CI 0.5–1.0, p-trend 0.001). Statistically significant inverse associations were found for all fruits listed in the questionnaire. RRs for quintiles of total fruit intake were 1.0, 0.7, 0.6, 0.6 and 0.8 respectively (p-trend < 0.0001). Protective effects of fruits and vegetables were stronger in current than in former smokers, and weaker for adenocarcinomas than for other types of tumors. Conclusions: Inverse associations with lung cancer are found for both vegetable and fruit intake, but no specific type of vegetable or fruit seems to be particularly responsible.
Starting Page	101
Ending Page	115
Page Count	15
File Format	PDF
ISSN	09575243
Journal	Cancer Causes & Control
Volume Number	11
Issue Number	2
e-ISSN	15737225
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2000-01-01
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Public Health/Gesundheitswesen Hematology Oncology Epidemiology
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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