NDLI: Negative BOLD in Sensory Cortices During Verbal Memory: A Component in Generating Internal Representations?

Content Provider	Springer Nature Link
Author	Azulay, Haim Striem, Ella Amedi, Amir
Copyright Year	2009
Abstract	People tend to close their eyes when trying to retrieve an event or a visual image from memory. However the brain mechanisms behind this phenomenon remain poorly understood. Recently, we showed that during visual mental imagery, auditory areas show a much more robust deactivation than during visual perception. Here we ask whether this is a special case of a more general phenomenon involving retrieval of intrinsic, internally stored information, which would result in crossmodal deactivations in other sensory cortices which are irrelevant to the task at hand. To test this hypothesis, a group of 9 sighted individuals were scanned while performing a memory retrieval task for highly abstract words (i.e., with low imaginability scores). We also scanned a group of 10 congenitally blind, which by definition do not have any visual imagery per se. In sighted subjects, both auditory and visual areas were robustly deactivated during memory retrieval, whereas in the blind the auditory cortex was deactivated while visual areas, shown previously to be relevant for this task, presented a positive BOLD signal. These results suggest that deactivation may be most prominent in task-irrelevant sensory cortices whenever there is a need for retrieval or manipulation of internally stored representations. Thus, there is a task-dependent balance of activation and deactivation that might allow maximization of resources and filtering out of non relevant information to enable allocation of attention to the required task. Furthermore, these results suggest that the balance between positive and negative BOLD might be crucial to our understanding of a large variety of intrinsic and extrinsic tasks including high-level cognitive functions, sensory processing and multisensory integration.
Starting Page	221
Ending Page	231
Page Count	11
File Format	PDF
ISSN	08960267
Journal	Brain Topography
Volume Number	21
Issue Number	3-4
e-ISSN	15736792
Language	English
Publisher	Springer US
Publisher Date	2009-03-27
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Multisensory integration Negative BOLD Intrinsic processing Crossmodal brain plasticity Verbal memory Crossmodal deactivation Neurology Psychiatry Neurosciences
Content Type	Text
Resource Type	Article
Subject	Neurology Anatomy Radiology, Nuclear Medicine and Imaging Neurology (clinical) Radiological and Ultrasound Technology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Negative BOLD Response to Interictal Epileptic Discharges in Focal Epilepsy

Identifying and Quantifying Multisensory Integration: A Tutorial Review

Possible anatomical pathways for short-latency multisensory integration processes in primary sensory cortices

Unimodal and Crossmodal Gradients of Spatial Attention: Evidence from Event-related Potentials

Not Just for Bimodal Neurons Anymore: The Contribution of Unimodal Neurons to Cortical Multisensory Processing

Audiovisual Non-Verbal Dynamic Faces Elicit Converging fMRI and ERP Responses

Behavioral Measures of Multisensory Integration: Bounds on Bimodal Detection Probability

Lateralization of Cerebral Activation in Auditory Verbal and Non-Verbal Memory Tasks Using Magnetoencephalography

Sound-Induced Flash Illusion is Resistant to Feedback Training

Negative BOLD in Sensory Cortices During Verbal Memory: A Component in Generating Internal Representations?

Similar Documents

Negative BOLD Response to Interictal Epileptic Discharges in Focal Epilepsy

Identifying and Quantifying Multisensory Integration: A Tutorial Review

Possible anatomical pathways for short-latency multisensory integration processes in primary sensory cortices

Unimodal and Crossmodal Gradients of Spatial Attention: Evidence from Event-related Potentials

Not Just for Bimodal Neurons Anymore: The Contribution of Unimodal Neurons to Cortical Multisensory Processing

Audiovisual Non-Verbal Dynamic Faces Elicit Converging fMRI and ERP Responses

Behavioral Measures of Multisensory Integration: Bounds on Bimodal Detection Probability

Lateralization of Cerebral Activation in Auditory Verbal and Non-Verbal Memory Tasks Using Magnetoencephalography

Sound-Induced Flash Illusion is Resistant to Feedback Training

Negative BOLD in Sensory Cortices During Verbal Memory: A Component in Generating Internal Representations?