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| Content Provider | Springer Nature Link |
|---|---|
| Author | Toth, Marton Faludi, Bela Wackermann, Jiri Czopf, Jozsef Kondakor, Istvan |
| Copyright Year | 2009 |
| Abstract | EEG background activity of patients with obstructive sleep apnea syndrome (OSAS, N = 25) was compared to that of normal controls (N = 14) to reflect alterations of brain electrical activity caused by chronic intermittent hypoxia in OSAS. Global and regional (left vs. right, anterior vs. posterior) measures of spatial complexity (Omega) were used to characterize the degree of spatial synchrony of EEG. Low resolution electromagnetic tomography (LORETA) was used to localize generators of EEG activity in separate frequency bands. Comparing patients to controls, lower Omega complexity was found globally and in the right hemisphere. Using LORETA, an increased medium frequency activity was seen bilaterally in the precuneus, paracentral and posterior cingulate cortex. These findings indicate that alterations caused by chronic hypoxia in brain electrical activity in regions associated with influencing emotional regulation, long-term memory and the default mode network. Global synchronization (lower Omega complexity) may indicate a significantly reduced number of relatively independent, parallel neural processes due to chronic global hypoxic state in apneic patients as well as over the right hemisphere. |
| Starting Page | 185 |
| Ending Page | 190 |
| Page Count | 6 |
| File Format | |
| ISSN | 08960267 |
| Journal | Brain Topography |
| Volume Number | 22 |
| Issue Number | 3 |
| e-ISSN | 15736792 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2009-08-27 |
| Publisher Place | Boston |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | LORETA Obstructive sleep apnea syndrome Omega complexity Quantitative EEG Posterior cingulate cortex Precuneus Posterior parietal cortex Neurology Psychiatry Neurosciences |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology Anatomy Radiology, Nuclear Medicine and Imaging Neurology (clinical) Radiological and Ultrasound Technology |
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