NDLI: Bio-hybrid muscle cell-based actuators

Content Provider	Springer Nature Link
Author	Ricotti, Leonardo Menciassi, Arianna
Copyright Year	2012
Abstract	Actuation is an essential function of any artificial or living machine, allowing its movement and its interaction with the surrounding environment. Living muscles have evolved over millions of years within animals as nature’s premier living generators of force, work and power, showing unique characteristics in comparison with standard artificial actuators. Current actuation technologies actually represent a real bottleneck in many robotics and ICT applications, including the bio-inspired ones. Main limitations involve inertia and backdrivability, stiffness control and power consumption. The development of novel actuators able to better mimic or even to overcome living muscle performances would open new horizons in robotics and ICT technologies: these components would allow the raise of a new generation of machines, with life-like movements and outstanding performances. An innovative solution to achieve this goal is represented by the merging between artificial and living entities, towards the realization of bio-hybrid devices. The aim of the present article is to describe the scientific and technological efforts made by researchers in the last two decades to achieve cell- or tissue-based actuators, with the dream of matching or outperforming natural muscles and to efficiently power micro- and mini-devices. The main challenges connected to the development of a cell-based actuator are highlighted and the most recent solutions to this scientific/technological problem are depicted, reporting advantages and drawbacks of each single approach. Future perspectives are also described, envisioning bio-hybrid actuators as key components of a new generation of machines able to show life-like movements and behaviors.
Starting Page	987
Ending Page	998
Page Count	12
File Format	PDF
ISSN	13872176
Journal	Biomedical Microdevices
Volume Number	14
Issue Number	6
e-ISSN	15728781
Language	English
Publisher	Springer US
Publisher Date	2012-09-08
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Bio-hybrid systems Cell-based actuators Living machines Muscle tissue engineering Biophysics and Biological Physics Biomedical Engineering Nanotechnology Engineering Fluid Dynamics
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Molecular Biology Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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