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Metabolic pathways for lipid synthesis under nitrogen stress in Chlamydomonas and Nannochloropsis

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Metabolic pathways for lipid synthesis under nitrogen stress in Chlamydomonas and Nannochloropsis

Content Provider	Springer Nature Link
Author	Banerjee, Avik Maiti, Subodh K. Guria, Chandan Banerjee, Chiranjib
Copyright Year	2016
Abstract	Microalgae are currently being considered as a clean, sustainable and renewable energy source. Enzymes that catalyse the metabolic pathways for biofuel production are specific and require strict regulation and co-ordination. Thorough knowledge of these key enzymes along with their regulatory molecules is essential to enable rational metabolic engineering, to drive the metabolic flux towards the desired metabolites of importance. This paper reviews two key enzymes that play their role in production of bio-oil: DGAT (acyl–CoA:diacylglycerol acyltransferase) and PDAT (phospholipid:diacylglycerol acyltransferase). It also deals with the transcription factors that control the enzymes while cell undergoes a metabolic shift under stress. The paper also discusses the association of other enzymes and pathways that provide substrates and precursors for oil accumulation. Finally a futuristic solution has been proposed about a synthetic algal cell platform that would be committed towards biofuel synthesis.
Starting Page	1
Ending Page	11
Page Count	11
File Format	PDF
ISSN	01415492
Journal	Biotechnology Letters
Volume Number	39
Issue Number	1
e-ISSN	15736776
Language	English
Publisher	Springer Netherlands
Publisher Date	2016-09-21
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Acyl–CoA:diacylglycerolacyltransferase Lipid regulators Microalgae Phopholipid diacylglycerol acyltransferase Synthetic cell Triacylglycerol Microbiology Biotechnology Applied Microbiology Biochemistry
Content Type	Text
Resource Type	Article
Subject	Medicine Bioengineering Applied Microbiology and Biotechnology Biotechnology

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Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae

Diacylglycerol Acyltransferase-2 (DGAT2) and Monoacylglycerol Acyltransferase-2 (MGAT2) Interact to Promote Triacylglycerol Synthesis

Identification of gene transcripts involved in lipid biosynthesis in Chlamydomonas reinhardtii under nitrogen, iron and sulfur deprivation

Accelerated triacylglycerol production and altered fatty acid composition in oleaginous microalga Neochloris oleoabundans by overexpression of diacylglycerol acyltransferase 2

Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae

Storage Lipid Synthesis Is Non-essential in Yeast

Nitrogen and sulfur deprivation differentiate lipid accumulation targets of Chlamydomonas reinhardtii

Nannochloropsis, a rich source of diacylglycerol acyltransferases for engineering of triacylglycerol content in different hosts

A type-I diacylglycerol acyltransferase modulates triacylglycerol biosynthesis and fatty acid composition in the oleaginous microalga, Nannochloropsis oceanica

Metabolic pathways for lipid synthesis under nitrogen stress in Chlamydomonas and Nannochloropsis

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Metabolic pathways for lipid synthesis under nitrogen stress in Chlamydomonas and Nannochloropsis