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| Content Provider | Springer Nature Link |
|---|---|
| Author | Chen, Zhilong Gao, Xin Lei, Ting Chen, Xiaodong Zhou, Lei Yu, An Lei, Peng Zhang, Rongrong Long, Huan Yang, Zaiqing |
| Copyright Year | 2011 |
| Abstract | Patatin-like phospholipases (PNPLAs) comprise a protein family whose members contain a conserved patatin-like domain with lipid acyl hydrolase activity. The cloning and characterization of full-length cDNAs of PNPLA3 and PNPLA4 in pigs is reported and, for the first time, an alternative splicing variant of porcine PNPLA4, which skips exon 5 of the normal transcript, was identified. Subsequently, tissue expression analysis by quantitative PCR indicated that porcine PNPLA3 was mainly expressed in both adipose and liver whereas porcine PNPLA4 was abundant in liver. Porcine PNPLA3 and PNPLA4 were assigned respectively to chromosome 5p11-p15 and Xp24. |
| Starting Page | 1327 |
| Ending Page | 1337 |
| Page Count | 11 |
| File Format | |
| ISSN | 01415492 |
| Journal | Biotechnology Letters |
| Volume Number | 33 |
| Issue Number | 7 |
| e-ISSN | 15736776 |
| Language | English |
| Publisher | Springer Netherlands |
| Publisher Date | 2011-03-13 |
| Publisher Place | Dordrecht |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Alternative splicing Chromosomal mapping Expression pattern Patatin-like phospholipases Biochemistry Microbiology Biotechnology Applied Microbiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Bioengineering Applied Microbiology and Biotechnology Biotechnology |
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