NDLI: Cloning, Expression Pattern, Chromosomal Localization, and Evolution Analysis of Porcine Gnaq, Gna11, and Gna14

Content Provider	Springer Nature Link
Author	Chen, Huaping Yao, Wenshu Jin, Dan Xia, Tao Chen, Xiaodong Lei, Ting Zhou, Lei Yang, Zaiqing
Copyright Year	2008
Abstract	The Gq class is one subfamily of the G protein α subunits multigene family. It comprises four genes: Gnaq, Gna11, Gna14, and Gna15. In mice and humans, the α subunit is an essential component of G protein interaction with receptors and effectors. We report here the cloning and characterization of porcine Gnaq, Gna11, and Gna14. We have cloned the full-length coding sequences of porcine Gnaq, Gna11, and Gna14 (1,080, 1,080, and 1,068 bp, respectively) and then mapped them chromosomally to regions 1q21-27, 2q21-24, and 1q21-27 by radiation hybrid mapping. Tissue distribution analysis indicated that Gnaq and Gna11 were coexpressed in liver, heart, muscle, spleen, adipose tissue, brain, and uterus, but Gna14 mRNA was detected only in kidney and lung. The phylogenetic trees reveal that porcine Gnaq, Gna11, and Gna14 are evolutionarily closer to their human homologs. This is the first report of molecular cloning and characterization of porcine Gnaq, Gna11, and Gna14, which will be helpful for further understanding of the physiological role of Gq class genes in pigs.
Starting Page	398
Ending Page	405
Page Count	8
File Format	PDF
ISSN	00062928
Journal	Biochemical Genetics
Volume Number	46
Issue Number	7-8
e-ISSN	15734927
Language	English
Publisher	Springer US
Publisher Date	2008-03-11
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Gnaq Gna11 Gna14 Molecular cloning Porcine Medical Microbiology Zoology Biochemistry Human Genetics
Content Type	Text
Resource Type	Article
Subject	Genetics Medicine Biochemistry Molecular Biology Ecology, Evolution, Behavior and Systematics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Cloning, expression pattern, chromosomal localization, and evolution analysis of Porcine gnaq, gna11, and gna14.

Molecular Characteristics of the Porcine TIMD4 Gene and Its Association Analysis

Molecular Cloning and Expression Analysis of Porcine Ghrelin O-Acyltransferase

Molecular Cloning, Mapping, and Polymorphism of the Porcine SCG2 gene

Cloning, Tissue Expression Pattern, and Chromosome Location of a Novel Human Gene BRI3BP

Analysis of Expressed Sequence Tags in Porcine Uterus Tissue

Sequence Characterization, Polymorphism, and Chromosomal Localizations of the Porcine Capz Genes

Molecular Cloning, Expression, and Chromosomal Mapping of the Porcine CDC-2-Like Kinase 1 (CLK1) Gene

Molecular Cloning, Mapping, and Expression Analysis of the EIF4A2 Gene in Pig

Cloning, Expression Pattern, Chromosomal Localization, and Evolution Analysis of Porcine Gnaq, Gna11, and Gna14

Similar Documents

Cloning, expression pattern, chromosomal localization, and evolution analysis of Porcine gnaq, gna11, and gna14.

Molecular Characteristics of the Porcine TIMD4 Gene and Its Association Analysis

Molecular Cloning and Expression Analysis of Porcine Ghrelin O-Acyltransferase

Molecular Cloning, Mapping, and Polymorphism of the Porcine SCG2 gene

Cloning, Tissue Expression Pattern, and Chromosome Location of a Novel Human Gene BRI3BP

Analysis of Expressed Sequence Tags in Porcine Uterus Tissue

Sequence Characterization, Polymorphism, and Chromosomal Localizations of the Porcine Capz Genes

Molecular Cloning, Expression, and Chromosomal Mapping of the Porcine CDC-2-Like Kinase 1 (CLK1) Gene

Molecular Cloning, Mapping, and Expression Analysis of the EIF4A2 Gene in Pig

Cloning, Expression Pattern, Chromosomal Localization, and Evolution Analysis of Porcine Gnaq, Gna11, and Gna14