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| Content Provider | Springer Nature Link |
|---|---|
| Author | Udut, V. V. Khazav, V. A. Gurto, R. V. Borodulina, E. V. Postnikova, Yu. E. Gribov, S. A. Ivav, A. V. Tarasova, I. V. Demchenko, E. Yu. |
| Copyright Year | 2007 |
| Abstract | Individual pharmacokinetic profiles of captopril and capoten depend on adaptation reactions of the organism and variants of autonomic regulations of functions. Maximum bioavailability and peak concentrations of captopril in blood plasma were observed during phenotypically determined physiological adaptation reactions of the general adaptation syndrome (“training” and “zone of mild activation”) and decreased during reactions of “enhanced activation” and “hyperactivation” The observed relationships can be explained by the existing gradient of sympathetic influences in the regulation of variants of adaptation reactions. |
| Starting Page | 38 |
| Ending Page | 41 |
| Page Count | 4 |
| File Format | |
| ISSN | 00074888 |
| Journal | Bulletin of Experimental Biology and Medicine |
| Volume Number | 143 |
| Issue Number | 1 |
| e-ISSN | 15738221 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2007-01-01 |
| Publisher Place | Boston |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | pharmacokinetic profile capoten captopril phases of adaptation reactions autonomic regulation of functions Biomedicine general Internal Medicine Cell Biology Pathology Laboratory Medicine |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Biochemistry, Genetics and Molecular Biology |
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