NDLI: Mechanisms of Hyperglycemic Effect of Calcitonin

Content Provider	Springer Nature Link
Author	Butakova, S. S. zdrachev, A. D.
Copyright Year	2011
Abstract	We studied the effect of calcitonin on blood glucose level, total calcium content, and the main stages of carbohydrate metabolism: absorption in the intestine, transport from the blood to tissues, tissue sensitivity to insulin in the whole organism, glycogen content, and activity of glucose-6-phosphate dehydrogenase and lactate dehydrogenase in the liver. A hyperglycemic effect of calcitonin was demonstrated, a close negative correlation was found between glucose level and total calcium content (r=-0.834, p<0.02). Calcitonin had no effect on glucose absorption in the small intestine and its transport from the blood to tissues (glucose consumption by peripheral tissues at the organism level), but reduced glycogen content in the liver and increased activities of glucose-6-phosphate dehydrogenase and lactate dehydrogenase.
Starting Page	320
Ending Page	323
Page Count	4
File Format	PDF
ISSN	00074888
Journal	Bulletin of Experimental Biology and Medicine
Volume Number	150
Issue Number	3
e-ISSN	15738221
Language	English
Publisher	Springer US
Publisher Date	2011-01-27
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	calcitonin glucose glycogenolysis, glucose-6-phosphate dehydrogenase lactate dehydrogenase Laboratory Medicine Pathology Cell Biology Internal Medicine Biomedicine general
Content Type	Text
Resource Type	Article
Subject	Medicine Biochemistry, Genetics and Molecular Biology

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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