NDLI: β-Carotene-containing preparations enhance antioxidant potential of the liver and myocardium

Content Provider	Springer Nature Link
Author	Tikhaze, A. K. Kovalova, G. G. Lankin, V. Z.
Copyright Year	1999
Abstract	The effects of β-carotene-containing food additives carinate and carinate CD on the antioxidant potential of rat liver and myocardium were examined. Daily oral administration of these drugs in doses equal to 0.4 and 14 mg/kg β-carotene inhibited ascorbate-dependent peroxidation of endogenous lipids in hepatocytes and cardiomyocytes 1.5–6.5- and 1.5–40-fold, respectively, depending on β-carotene form and dose. Carinate CD containing a complex of β—carotene with β-cyclodextrin was a more potent inhibitor of lipid peroxidation in the liver and myocardium than carinate containing free β-carotene. β-Carotene-containing food additives can be recommended for the prophylaxis of cardiovascular, oncological, and other diseases.
Starting Page	939
Ending Page	941
Page Count	3
File Format	PDF
ISSN	00074888
Journal	Bulletin of Experimental Biology and Medicine
Volume Number	128
Issue Number	3
e-ISSN	15738221
Language	English
Publisher	Kluwer Academic Publishers-Plenum Publishers
Publisher Date	1999-01-01
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	β-carotene antioxidants prooxidants lipids free radical oxidation Biomedicine general Laboratory Medicine Internal Medicine Pathology Cell Biology
Content Type	Text
Resource Type	Article
Subject	Medicine Biochemistry, Genetics and Molecular Biology

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β-Carotene-containing preparations enhance antioxidant potential of the liver and myocardium