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| Content Provider | Springer Nature Link |
|---|---|
| Author | Sibiryak, S. V. Sergeeva, S. A. Khlopushina, T. G. Kurchatova, N. N. Yusupova, R. Sh. |
| Copyright Year | 1998 |
| Abstract | The study explores the effect of lipopolysaccharides of various composition from Gram-negative bacteria on phagocytic activity and oxygen-dependent metabolism of macrophages, intensity of lipid peroxidation, and activity of microsomal enzymes in mouse liver, and production of interleukin-1 and tumor necrosis factor by cultured peripheral blood mononuclears. It is found that the magnitude of inhibiting effect of lipopolysaccharides on microsomal oxidation is a mirror reflection of the degree of their prooxidant effect and activation of phagocytic and secretory macrophage functions, which confirms tight coupling of these processes under conditions of acute phase response. |
| Starting Page | 159 |
| Ending Page | 162 |
| Page Count | 4 |
| File Format | |
| ISSN | 00074888 |
| Journal | Bulletin of Experimental Biology and Medicine |
| Volume Number | 125 |
| Issue Number | 2 |
| e-ISSN | 15738221 |
| Language | English |
| Publisher | Kluwer Academic Publishers-Plenum Publishers |
| Publisher Date | 1998-01-01 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | bacterial lipopolysaccharides microsomal oxidation macrophage activity Biomedicine general Laboratory Medicine Internal Medicine Pathology Cell Biology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Biochemistry, Genetics and Molecular Biology |
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