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  1. Bulletin of Experimental Biology and Medicine
  2. Bulletin of Experimental Biology and Medicine : Volume 129
  3. Bulletin of Experimental Biology and Medicine : Volume 129, Issue 5, May 2000
  4. Mechanisms of immunotoxic effects of acrylonitrile
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Bulletin of Experimental Biology and Medicine : Volume 162
Bulletin of Experimental Biology and Medicine : Volume 161
Bulletin of Experimental Biology and Medicine : Volume 160
Bulletin of Experimental Biology and Medicine : Volume 159
Bulletin of Experimental Biology and Medicine : Volume 158
Bulletin of Experimental Biology and Medicine : Volume 157
Bulletin of Experimental Biology and Medicine : Volume 156
Bulletin of Experimental Biology and Medicine : Volume 155
Bulletin of Experimental Biology and Medicine : Volume 154
Bulletin of Experimental Biology and Medicine : Volume 153
Bulletin of Experimental Biology and Medicine : Volume 152
Bulletin of Experimental Biology and Medicine : Volume 151
Bulletin of Experimental Biology and Medicine : Volume 150
Bulletin of Experimental Biology and Medicine : Volume 149
Bulletin of Experimental Biology and Medicine : Volume 148
Bulletin of Experimental Biology and Medicine : Volume 147
Bulletin of Experimental Biology and Medicine : Volume 146
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Bulletin of Experimental Biology and Medicine : Volume 144
Bulletin of Experimental Biology and Medicine : Volume 143
Bulletin of Experimental Biology and Medicine : Volume 142
Bulletin of Experimental Biology and Medicine : Volume 141
Bulletin of Experimental Biology and Medicine : Volume 140
Bulletin of Experimental Biology and Medicine : Volume 139
Bulletin of Experimental Biology and Medicine : Volume 138
Bulletin of Experimental Biology and Medicine : Volume 137
Bulletin of Experimental Biology and Medicine : Volume 136
Bulletin of Experimental Biology and Medicine : Volume 135
Bulletin of Experimental Biology and Medicine : Volume 134
Bulletin of Experimental Biology and Medicine : Volume 133
Bulletin of Experimental Biology and Medicine : Volume 132
Bulletin of Experimental Biology and Medicine : Volume 131
Bulletin of Experimental Biology and Medicine : Volume 130
Bulletin of Experimental Biology and Medicine : Volume 129
Bulletin of Experimental Biology and Medicine : Volume 129, Issue 6, June 2000
Bulletin of Experimental Biology and Medicine : Volume 129, Issue 5, May 2000
Metabolism of androgens in rat pituitary gland and hypothalamus: Catabolism of dihydrotestosterone or transformation of androgen signal?
Chronic administration of interferon-α decreases blood pressure and heart rate in rats
Variability of the rhythm of isolated rat heart
Effect of akatinol (Memantine) in central spinal pain syndrome
Peculiarities of ischemic cardiac arrhythmias in cats against the background of stimulation of sensorimotor cortex and administration of selective opiate receptor agonists
Sex differences in endothelium-dependent reactions of rabbit arteries to elevated blood flow
Urokinase stimulates differentiation of fibroblasts into myofibroblasts and their proliferation in damaged adventitia
Thyroid hormones as regulators of binding capacity of corticosteroid-binding globulin in rats subjected to acute immobilization stress
Role of volume-conductor properties of muscles in the formation of evoked contractions during stimulating electrical impedance myography
Ability of peritoneal exudate cells to trigger various mechanisms of erythroid differentiation at different terms after massive blood loss in mice
Effects of 17β-estradiol and its isomer 17α-estradiol on learning in rats with chronic cholinergic deficiency in the brain
Involvement of bone marrow fibroblasts in the recovery of granulocytopoiesis after cytostatic-induced myelosuppression
Hypertrophic synapses as a factor of formation of persistent pathological centers in the brain in the late postresuscitation period
Time course of malonic dialdehyde and α-tocopherol in rat pancreas during the first hours of acute pancreatitis
Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells
Glutathione S-transferase activity in the liver in acute pancreatitis at various terms of disease and during treatment with inducers
Effect of cyclic GABA derivative TZ-146 on the content of neurotransmitters in rat brain stem
Mechanisms of immunotoxic effects of acrylonitrile
Proportional criterion of metabolic activity and fundamentals of drug dosage
Role of Corticosterone in realization of immunosuppressive effects in acute poisoning with toxic chemicals
Collagenolytic protease preparations from invertebrates: Experimental study of acute and chronic toxicity
Changes in thermonociceptive thresholds and the role of enkephalinase A in homeostasis in morphine-tolerant rat offspring
Adrenergic regulation of phagocytic activity of peripheral blood neutrophils, monocytes, and eosinophils in stressed rats
Effect of semisynthetic analog of α1-acid glycoprotein on immunomodulatory and antiinflammatory activity of natural glycoproteinglycoprotein on immunomodulatory and antiinflammatory activity of natural glycoprotein
Effect of peroxidase on the development of experimental leprosy in mice after intraplantar infection
Multidimensional assessment of differences in monoamine metabolism in C57Bl/6 and BALB/c mice
Isolation and partial characterization of cDNA clone of human ceruloplasmin receptor
Leptin and apoptosis inhibitor soluble fas antigen in the serum of patients with osteosarcoma and neuroectodermal bone tumors
Use of cultured human fibroblasts for rapid evaluation of cytotoxic effects of bioactive substances
Neurotransmitter bioamine supply of thymic and lymph node structures during treatment with somatotropic hormone
Experimental morphological analysis of surgical bypassing of the uveal tract
Initial stage of vascular bed development in telencephalon of human embryo
Bulletin of Experimental Biology and Medicine : Volume 129, Issue 4, April 2000
Bulletin of Experimental Biology and Medicine : Volume 129, Issue 3, March 2000
Bulletin of Experimental Biology and Medicine : Volume 129, Issue 2, February 2000
Bulletin of Experimental Biology and Medicine : Volume 129, Issue 1, January 2000
Bulletin of Experimental Biology and Medicine : Volume 128
Bulletin of Experimental Biology and Medicine : Volume 127
Bulletin of Experimental Biology and Medicine : Volume 126
Bulletin of Experimental Biology and Medicine : Volume 125
Bulletin of Experimental Biology and Medicine : Volume 124
Bulletin of Experimental Biology and Medicine : Volume 123

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Mechanisms of immunotoxic effects of acrylonitrile

Content Provider Springer Nature Link
Author Zabrodskii, P. F. Kirichuk, V. F. Germanchuk, V. G. Belikov, V. G.
Copyright Year 2000
Abstract Cholinesterase reactivator dipyroxime and hydrogen cyanide antidote anticyan partially restore cell and humoral immune response in mice after acute acrylonitrile poisoning (0.5 LD50). When used in combination these drugs virtually completely prevented the suppression of immune reactions. The main mechanism of immunotoxic effect of acrylonitrile is mediated through inhibition of T lymphocyte esterases and a3 component of cytochromec oxidase of immunocyte mitochondrial respiration enzymes, which is important for prevention and treatment of immune disturbances caused by this toxin.
Starting Page 463
Ending Page 465
Page Count 3
File Format PDF
ISSN 00074888
Journal Bulletin of Experimental Biology and Medicine
Volume Number 129
Issue Number 5
e-ISSN 15738221
Language English
Publisher Kluwer Academic Publishers-Plenum Publishers
Publisher Date 2000-01-01
Publisher Place New York
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword acrylonitrile immune response delayed type hypersensitivity α-naphthylbutyrate esterase Biomedicine general Laboratory Medicine Internal Medicine Pathology Cell Biology
Content Type Text
Resource Type Article
Subject Medicine Biochemistry, Genetics and Molecular Biology
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