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  1. Bulletin of Experimental Biology and Medicine
  2. Bulletin of Experimental Biology and Medicine : Volume 153
  3. Bulletin of Experimental Biology and Medicine : Volume 153, Issue 2, June 2012
  4. Absolute Bioavailability of Himantane in Rabbits
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Bulletin of Experimental Biology and Medicine : Volume 162
Bulletin of Experimental Biology and Medicine : Volume 161
Bulletin of Experimental Biology and Medicine : Volume 160
Bulletin of Experimental Biology and Medicine : Volume 159
Bulletin of Experimental Biology and Medicine : Volume 158
Bulletin of Experimental Biology and Medicine : Volume 157
Bulletin of Experimental Biology and Medicine : Volume 156
Bulletin of Experimental Biology and Medicine : Volume 155
Bulletin of Experimental Biology and Medicine : Volume 154
Bulletin of Experimental Biology and Medicine : Volume 153
Bulletin of Experimental Biology and Medicine : Volume 153, Issue 6, October 2012
Bulletin of Experimental Biology and Medicine : Volume 153, Issue 5, September 2012
Bulletin of Experimental Biology and Medicine : Volume 153, Issue 4, August 2012
Bulletin of Experimental Biology and Medicine : Volume 153, Issue 3, July 2012
Bulletin of Experimental Biology and Medicine : Volume 153, Issue 2, June 2012
Respiratory Response to Microinjections of GABA and Penicillin into Various Parts of the Ventral Respiratory Group
Behavioral Effects of Original Tetrapeptide, an Analog of N-Terminal Nociceptin Fragment
Effect of Single and Repeated Injections of Selective D2-Antagonist Clebopride on Maternal Behavior of Albino Rats
Activity of the Inflammatory Process in Different Types of Unstable Atherosclerotic Plaques
Mechanisms for Vascular Effects of Androgens in Normotensive and Hypertensive Rats
Effect of Taurine on the Proteomic Profile of the Cytosolic and Microsomal Fractions of Rat Hepatocytes during Ontogeny
Heterogeneity of Left Ventricular Cardiomyocytes from Rat Heart
Theory of Intercellular Communication in the Development of Endothelial Dysfunction
Absolute Bioavailability of Himantane in Rabbits
Changes in Electrokinetic Properties of Erythrocytes under the Influence of Pentoxifylline and New Hemorheologically Active Substances
Study of Wound-Healing Activity of Bioregulators Isolated from Eye Tissues and Bovine Serum in the Model of Experimental Corneal Injury in Rabbits In Vivo
Effect of Regular Physical Training on Hemopoiesis in Experimental Animals
In Vitro Expression of Vascular Endothelial Growth Factor and Its Receptors by Placental Macrophages
Telomere Lengthening in CD8+ Cells in Polyclonal In Vitro Stimulation is Associated with an Increase in Protein Content of Catalytic Subunit of Telomerase (hTERT)
Structural and Functional Changes in Pulmonary Macrophages and Lungs of Mice Infected with Influenza Virus A/H5N1 A/goose/Krasnoozerskoye/627/05
New Adamantane Derivatives Can Overcome Resistance of Influenza A(H1N1)pdm2009 and A(H3N2) Viruses to Remantadine
Expression of TLR9 and BD-2 Protein Genes in Corneal Cells of Mice of Different Strains with Herpetic Keratitis
Modification of the Testicular Function in Laboratory Male Mice during Social Interactions: Effect of Female Presence
Analysis of Expression of Genes Involved in Immune Response Modulation in Silent Multipotent Mesenchymal Stromal Cells
Serum Immunoglobulin Free Light Chains in Patients with Monoclonal Gammapathies
Molecular Cellular Mechanisms of Peptide Regulation of Melatonin Synthesis in Pinealocyte Culture
Proliferative Activity and Viability of Fibroblast and Glioblastoma Cell on Various Types of Carbon Nanotubes
Pharmacology of Somatrotropin Pegylated by Electron-Beam Synthesis Nanotechnology
Physiological and Biomechanical Characteristics of the Kick and Goal Techniques of Football Players
Effect of Esophagoplasty on Structural Reorganization of Colon Transplant
Response of Glandular Organs to Experimental Macroglossia
Expression of Renal Crystallization Inhibitors in Experimental Nephrolithiasis
Role of Sexually-Transmitted Infections in the Structural and Functional Reorganization of the Prostate
Experimental Morphological Study of the Effects of Subchondral Tunnelization and Bone Marrow Stimulation on Articular Cartilage Regeneration
Bulletin of Experimental Biology and Medicine : Volume 153, Issue 1, May 2012
Bulletin of Experimental Biology and Medicine : Volume 152
Bulletin of Experimental Biology and Medicine : Volume 151
Bulletin of Experimental Biology and Medicine : Volume 150
Bulletin of Experimental Biology and Medicine : Volume 149
Bulletin of Experimental Biology and Medicine : Volume 148
Bulletin of Experimental Biology and Medicine : Volume 147
Bulletin of Experimental Biology and Medicine : Volume 146
Bulletin of Experimental Biology and Medicine : Volume 145
Bulletin of Experimental Biology and Medicine : Volume 144
Bulletin of Experimental Biology and Medicine : Volume 143
Bulletin of Experimental Biology and Medicine : Volume 142
Bulletin of Experimental Biology and Medicine : Volume 141
Bulletin of Experimental Biology and Medicine : Volume 140
Bulletin of Experimental Biology and Medicine : Volume 139
Bulletin of Experimental Biology and Medicine : Volume 138
Bulletin of Experimental Biology and Medicine : Volume 137
Bulletin of Experimental Biology and Medicine : Volume 136
Bulletin of Experimental Biology and Medicine : Volume 135
Bulletin of Experimental Biology and Medicine : Volume 134
Bulletin of Experimental Biology and Medicine : Volume 133
Bulletin of Experimental Biology and Medicine : Volume 132
Bulletin of Experimental Biology and Medicine : Volume 131
Bulletin of Experimental Biology and Medicine : Volume 130
Bulletin of Experimental Biology and Medicine : Volume 129
Bulletin of Experimental Biology and Medicine : Volume 128
Bulletin of Experimental Biology and Medicine : Volume 127
Bulletin of Experimental Biology and Medicine : Volume 126
Bulletin of Experimental Biology and Medicine : Volume 125
Bulletin of Experimental Biology and Medicine : Volume 124
Bulletin of Experimental Biology and Medicine : Volume 123

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Absolute Bioavailability of Himantane in Rabbits

Content Provider Springer Nature Link
Author Litvin, E. A. Bastrygin, D. V. Kolyvav, G. B. Alekseev, K. V. Zherdev, V. P.
Copyright Year 2012
Abstract Pharmacokinetic parameters of himantane and its metabolites in the blood plasma of rabbits were compared after single administration of himantane solution in a dose of 25 mg intravenously and 100 mg orally. It was established that the original substance is characterized by low absolute bioavailability (7.95%). Himantane is subjected to first-pass effect and is extensively metabolized in the liver to metabolites with m/z 266 and 250.
Starting Page 206
Ending Page 208
Page Count 3
File Format PDF
ISSN 00074888
Journal Bulletin of Experimental Biology and Medicine
Volume Number 153
Issue Number 2
e-ISSN 15738221
Language English
Publisher Springer US
Publisher Date 2012-07-11
Publisher Place Boston
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword himantane pharmacokinetics absolute bioavailability Biomedicine general Laboratory Medicine Pathology Internal Medicine Cell Biology
Content Type Text
Resource Type Article
Subject Medicine Biochemistry, Genetics and Molecular Biology
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