NDLI: Patterns of TRPM7 Expression in Hypothalamic and Hippocampal Neurons in Modeling of Nutritional Magnesium Defi ciency

Content Provider	Springer Nature Link
Author	Smirv, A. V. Spasov, A. A. Shmidt, M. V. Snigur, G. L. Evsyukov, O. Yu. Zheltova, A. A.
Copyright Year	2014
Abstract	Patterns of expression of TRPM7, the major cellular magnesium transporters in neurons of the hypothalamic region and hippocampus, were studied immunohistochemically. Multidirectional nature and different levels of the expression of the above antigen were revealed during modeled magnesium defi ciency with regard to structural and functional features of neuron organization in the hypothalamic paraventricular and supraoptic nuclei as well as hippocampal fi eld CA1 and CA3. Changes in the structural characteristics of neurons in the studied areas (absolute and relative indicators) and TRPM7 expression patterns were quantitatively analyzed considering the data on the role of the studied antigen in magnesium homeostasis, cell damage, and compensation.
Starting Page	736
Ending Page	739
Page Count	4
File Format	PDF
ISSN	00074888
Journal	Bulletin of Experimental Biology and Medicine
Volume Number	156
Issue Number	6
e-ISSN	15738221
Language	English
Publisher	Springer US
Publisher Date	2014-05-03
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	hypothalamus hippocampus expression magnesium receptor Biomedicine general Internal Medicine Cell Biology Pathology Laboratory Medicine
Content Type	Text
Resource Type	Article
Subject	Medicine Biochemistry, Genetics and Molecular Biology

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Patterns of TRPM7 Expression in Hypothalamic and Hippocampal Neurons in Modeling of Nutritional Magnesium Defi ciency