NDLI: Neutron-capture therapy with ultra-cold neutrons

Content Provider	Springer Nature Link
Author	Arzumav, S. S. Bondarenko, L. N. Zagryadskii, V. A. Markovskii, D. V. Morozov, V. I. Strepetov, A. N. Chuvilin, D. Yu.
Copyright Year	2010
Abstract	The status of neutron-capture therapy of malignant tumors and its problems – damage to healthy tissue as a result of neutron transport to the irradiation location and presence in the therapeutic beam of a background consisting of γ rays and fast neutrons – are presented. To solve these problems, the authors have proposed using ultracold neutrons with energy less than 10–7 eV, whose unique capability is to undergo total reflection from the surface of a condensed substance at any angle of incidence. Numerous works have demonstrated that such neutrons can be transported along neutron guides. The cross section for inelastic scattering of neutrons by hydrogen-containing substances – water, ethyl alcohol, and biological tissue – has been measured in an IR-8 beam of ultracold and very cold neutrons. At temperature 200–300 K, the experimental data are in very good agreement with calculations, but as temperature decreases further a discrepancy appears, which could be due to the inaccuracy of the model spectra of the oscillations hydrogen-containing substances used in the calculations. The use of ultracold neutrons opens up new possibilities of neutron-capture therapy for treating malignant tumors localized in body cavities or organs.
Starting Page	22
Ending Page	33
Page Count	12
File Format	PDF
ISSN	10634258
Journal	Atomic Energy
Volume Number	109
Issue Number	1
e-ISSN	15738205
Language	English
Publisher	Springer US
Publisher Date	2010-11-17
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Nuclear Chemistry Nuclear Engineering Nuclear Physics, Heavy Ions, Hadrons
Content Type	Text
Resource Type	Article
Subject	Nuclear Energy and Engineering

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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