NDLI: Computational Study of Fluid Mechanical Disturbance Induced by Endovascular Stents

Content Provider	Springer Nature Link
Author	Seo, Taewon Schachter, Levanto G. Barakat, Abdul I.
Copyright Year	2005
Abstract	Arterial restenosis following stent deployment may be influenced by the local flow environment within and around the stent. We have used computational fluid dynamics to investigate the flow field in the vicinity of model stents positioned within straight and curved vessels. Our simulations have revealed the presence of flow separation and recirculation immediately downstream of stents. In steady flow within straight vessels, the extent of flow disturbance downstream of the stent increases with both Reynolds number and stent wire thickness but is relatively insensitive to stent interwire spacing. In curved vessels, flow disturbance downstream of the stent occurs along both the inner and outer vessel walls with the extent of disturbance dependent on the angle of vessel curvature. In pulsatile flow, the regions of flow disturbance periodically increase and decrease in size. Non-Newtonian fluid properties lead to a modest reduction in flow disturbance downstream of the stent. In more realistic stent geometries such as stents modeled as spirals or as intertwined rings, the nature of stent-induced flow disturbance is exquisitely sensitive to stent design. These results provide an understanding of the flow physics in the vicinity of stents and suggest strategies for stent design optimization to minimize flow disturbance.
Starting Page	444
Ending Page	456
Page Count	13
File Format	PDF
ISSN	00906964
Journal	Annals of Biomedical Engineering
Volume Number	33
Issue Number	4
e-ISSN	15739686
Language	English
Publisher	Kluwer Academic Publishers-Plenum Publishers
Publisher Date	2005-01-01
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Restenosis Flow separation Flow recirculation Intravascular devices CFD Atherosclerosis Intimal hyperplasia Biochemistry Mechanics Biophysics/Biomedical Physics Vibration, Dynamical Systems, Control Biomedical Engineering
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering

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