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| Content Provider | Springer Nature Link |
|---|---|
| Author | Erickson, Jonathan C. O’Grady, Gregory Du, Peng Obioha, Chibuike Qiao, Wenlian Richards, William O. Bradshaw, L. Alan Pullan, Andrew J. Cheng, Leo K. |
| Copyright Year | 2009 |
| Abstract | High resolution (HR) multi-electrode mapping is increasingly being used to evaluate gastrointestinal slow wave behaviors. To create the HR activation time (AT) maps from gastric serosal electrode recordings that quantify slow wave propagation, it is first necessary to identify the AT of each individual slow wave event. Identifying these ATs has been a time consuming task, because there has previously been no reliable automated detection method. We have developed an automated AT detection method termed falling-edge, variable threshold (FEVT) detection. It computes a detection signal transform to accentuate the high ‘energy’ content of the falling edges in the serosal recording, and uses a running median estimator of the noise to set the time-varying detection threshold. The FEVT method was optimized, validated, and compared to other potential algorithms using in vivo HR recordings from a porcine model. FEVT properly detects ATs in a wide range of waveforms, making its performance substantially superior to the other methods, especially for low signal-to-noise ratio (SNR) recordings. The algorithm offered a substantial time savings (>100 times) over manual-marking whilst achieving a highly satisfactory sensitivity (0.92) and positive-prediction value (0.89). |
| Starting Page | 1511 |
| Ending Page | 1529 |
| Page Count | 19 |
| File Format | |
| ISSN | 00906964 |
| Journal | Annals of Biomedical Engineering |
| Volume Number | 38 |
| Issue Number | 4 |
| e-ISSN | 15739686 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2009-12-19 |
| Publisher Place | Boston |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Gastric electrical activity Gastric slow wave Activation time map High-resolution mapping Energy operator Biochemistry Mechanics Biophysics and Biological Physics Biomedical Engineering Biomedicine general |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biomedical Engineering |
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