NDLI: Numerical analysis of mixing performance in sinusoidal microchannels based on particle motion in droplets

Content Provider	Springer Nature Link
Author	Özkan, Alican Erdem, E. Yegân
Copyright Year	2015
Abstract	This numerical study was conducted to analyze and understand the parameters that affect the mixing performance of droplet-based flow in sinusoidal microfluidic channels. Finite element analysis was used for modeling fluid flow and droplet formation inside the microchannels via tracking interface between the two heterogeneous fluids along with multiple particle trajectories inside a droplet. The solutions of multiphase fluid flow and particle trajectories were coupled with each other so that drag on every single particle changed in every time step. To solve fluid motion in multiphase flow, level set method was used. Parametric study was repeated for different channel dimensions and different sinusoidal channel profiles. These results were compared with mixing in droplets inside a straight microchannel. Additionally, tracking of multiple particles inside a droplet was performed to simulate the circulating flow profile inside the droplets. Based on the calculation of the dispersion length, particle trajectories, and velocities inside droplets, it is concluded that having smaller channel geometries increases the mixing performance inside the droplet. This also shows that droplet-based fluid flow in microchannels is very suitable for performing chemical reactions inside droplets as it will occur faster. Moreover, narrower and sinusoidal microchannels showed better dispersion length difference compared to straight and wider microchannels.
Starting Page	1101
Ending Page	1108
Page Count	8
File Format	PDF
ISSN	16134982
Journal	Microfluidics and Nanofluidics
Volume Number	19
Issue Number	5
e-ISSN	16134990
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2015-08-22
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Droplet-based microfluidics Dispersion length Mixing performance Microfluidics Droplet formation Level set method Engineering Fluid Dynamics Biomedical Engineering Analytical Chemistry Nanotechnology and Microengineering
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Materials Chemistry Condensed Matter Physics Electronic, Optical and Magnetic Materials

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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