NDLI: Simulation of advanced microfluidic systems with dissipative particle dynamics

Content Provider	Springer Nature Link
Author	Steiner, Thomas Cupelli, Claudio Zengerle, Roland Santer, Mark
Copyright Year	2008
Abstract	Computational Fluid Dynamics (CFD) is widely and successfully used in standard design processes for microfluidic μTAS devices. But for an increasing number of advanced applications involving the dynamics of small groups of beads, blood cells or biopolymers in microcapillaries or sorting devices, novel simulation techniques are called for. Representing moving rigid or flexible extended dispersed objects poses serious difficulties for traditional CFD schemes. Meshless, particle-based simulation approaches, such as Dissipative Particle Dynamics (DPD) are suited for addressing these complicated flow problems with sufficient numerical efficiency. Objects can conveniently be represented as compound objects embedded seamlessly within an explicit model for the solvent. However, the application of DPD and related methods to realistic problems, in particular the design of microfluidics systems, is not well developed in general. With this work, we demonstrate how the method appears when used in practice, in the process of designing and simulating a specific microfluidic device, a microfluidic chamber representing a prototypical bead-based immunoassay developed in our laboratory (Glatzel et al. 2006a, b; Riegger et al. 2006).
Starting Page	307
Ending Page	323
Page Count	17
File Format	PDF
ISSN	16134982
Journal	Microfluidics and Nanofluidics
Volume Number	7
Issue Number	3
e-ISSN	16134990
Language	English
Publisher	Springer-Verlag
Publisher Date	2009-01-09
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Dissipative particle dynamics Simulation of microfluidic systems Lab on a chip Biomedical Engineering Engineering Fluid Dynamics
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Materials Chemistry Condensed Matter Physics Electronic, Optical and Magnetic Materials

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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