NDLI: ESI-MS response characteristics of a synthetic peptide

Content Provider	Springer Nature Link
Author	Zook, D. R. Forsmo Bruce, H. Briem, S.
Copyright Year	2000
Abstract	ESI-MS response characteristics of a proprietary synthetic peptide are briefly studied through variation of solution composition, buffer content, liquid flow and nebulizer temperature. In accordance with Kebarle'sion competition theory, decreasing buffer concentration was seen to be well correlated to improved ESI-MS response. In line with general expectation, increased mobile phase organic content and heightened nebulizer temperature improved response, presumably factors promoting droplet fission/ion release via lowered droplet surface tension and added thermal energy, respectively. In contrast to expectation, added sodium chloride resulted in a modest signal increase despite concomitant formation of sodium adduct. A similar signal enhancement effect has been previously reported for quaternary ammonium halides, attributed to a thinning in the charged droplet electric bi-layer thereby promoting ion release.
Starting Page	S60
Ending Page	S64
File Format	PDF
ISSN	00095893
Journal	Chromatographia
Volume Number	52
Issue Number	1
e-ISSN	16121112
Language	English
Publisher	Vieweg Verlag
Publisher Date	2000-01-01
Publisher Place	Wiesbaden
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Electrospray Mass spectrometry Synthetic peptide Analytical Chemistry Organic Chemistry Pharmacy Biochemistry Plant Sciences Measurement Science, Instrumentation
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Analytical Chemistry Biochemistry Clinical Biochemistry

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Peptide characterization by CE-ESI-MS with orthogonal spray

Sensitive and Selective LC–ESI–MS Analysis of Aesculin in Rat Plasma

CE-MS-MS of peptides using a novel orthogonal CE ESI sprayer and ion trap MS

Determination of Ranolazine in Rat Plasma by Liquid Chromatography–Electrospray Ionization Mass Spectrometry

Reversed Phase Continuous Full Filling CEC–ESI–MS

LC–ESI–MS Determination of Flupentixol in Human Plasma

Simultaneous Determination of Tramadol and Acetaminophen in Human Plasma by LC–ESI–MS

A Sensitive LC–ESI–MS–MS Method for the Determination of Huperzine A in Human Plasma: Method and Clinical Applications

On-line microdialysis-electrospray mass spectrometry for automated desalting of small-volume peptide samples

ESI-MS response characteristics of a synthetic peptide

Similar Documents

Peptide characterization by CE-ESI-MS with orthogonal spray

Sensitive and Selective LC–ESI–MS Analysis of Aesculin in Rat Plasma

CE-MS-MS of peptides using a novel orthogonal CE ESI sprayer and ion trap MS

Determination of Ranolazine in Rat Plasma by Liquid Chromatography–Electrospray Ionization Mass Spectrometry

Reversed Phase Continuous Full Filling CEC–ESI–MS

LC–ESI–MS Determination of Flupentixol in Human Plasma

Simultaneous Determination of Tramadol and Acetaminophen in Human Plasma by LC–ESI–MS

A Sensitive LC–ESI–MS–MS Method for the Determination of Huperzine A in Human Plasma: Method and Clinical Applications

On-line microdialysis-electrospray mass spectrometry for automated desalting of small-volume peptide samples

ESI-MS response characteristics of a synthetic peptide