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| Content Provider | Springer Nature Link | 
|---|---|
| Author | Patil, Dada Gautam, Manish Mishra, Sanjay Kulkarni, Prajakta Suresh, Karupothula Gairola, Sunil Jadhav, Suresh Patwardhan, Bhushan | 
| Copyright Year | 2009 | 
| Abstract | Tinospora cordifolia, known as Guduchi in Ayurveda, is a medicinal plant popular mainly for immunomodulatory activity. Its therapeutic activity may be attributed to protoberberine alkaloids such as jatrorrhizine, palmatine and berberine. A new, simple RP-LC-DAD method has been developed for separation, simultaneous identification and quantitative estimation of these protoberberine alkaloids in T. cordifolia extracts and formulations. The developed method was validated based on ICH-Q2B guidelines and was found to be accurate, precise and linear over a relatively wide range of concentrations (0.65–83.33 μg mL−1). This method can serve as a useful quality control tool for T. cordifolia and its formulations. | 
| Starting Page | 341 | 
| Ending Page | 345 | 
| Page Count | 5 | 
| File Format | |
| ISSN | 00095893 | 
| Journal | Chromatographia | 
| Volume Number | 71 | 
| Issue Number | 3-4 | 
| e-ISSN | 16121112 | 
| Language | English | 
| Publisher | Vieweg Verlag | 
| Publisher Date | 2009-12-15 | 
| Publisher Place | Wiesbaden | 
| Access Restriction | One Nation One Subscription (ONOS) | 
| Subject Keyword | Column liquid chromatography-diode array detection Protoberberine alkaloids Berberine, jatrorrhizine and palmatine Tinospora cordifolioa Measurement Science and Instrumentation Plant Sciences Biochemistry Pharmacy Organic Chemistry Analytical Chemistry | 
| Content Type | Text | 
| Resource Type | Article | 
| Subject | Organic Chemistry Analytical Chemistry Biochemistry Clinical Biochemistry | 
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