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  1. European Journal of Clinical Microbiology & Infectious Diseases
  2. European Journal of Clinical Microbiology & Infectious Diseases : Volume 16
  3. European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 3, March 1997
  4. Central venous catheter-related sepsis in a cohort of 366 hospitalised patients
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European Journal of Clinical Microbiology & Infectious Diseases : Volume 36
European Journal of Clinical Microbiology & Infectious Diseases : Volume 35
European Journal of Clinical Microbiology & Infectious Diseases : Volume 34
European Journal of Clinical Microbiology & Infectious Diseases : Volume 33
European Journal of Clinical Microbiology & Infectious Diseases : Volume 32
European Journal of Clinical Microbiology & Infectious Diseases : Volume 31
European Journal of Clinical Microbiology & Infectious Diseases : Volume 30
European Journal of Clinical Microbiology & Infectious Diseases : Volume 29
European Journal of Clinical Microbiology & Infectious Diseases : Volume 28
European Journal of Clinical Microbiology & Infectious Diseases : Volume 27
European Journal of Clinical Microbiology & Infectious Diseases : Volume 26
European Journal of Clinical Microbiology & Infectious Diseases : Volume 25
European Journal of Clinical Microbiology & Infectious Diseases : Volume 24
European Journal of Clinical Microbiology & Infectious Diseases : Volume 23
European Journal of Clinical Microbiology & Infectious Diseases : Volume 22
European Journal of Clinical Microbiology & Infectious Diseases : Volume 21
European Journal of Clinical Microbiology & Infectious Diseases : Volume 20
European Journal of Clinical Microbiology & Infectious Diseases : Volume 19
European Journal of Clinical Microbiology & Infectious Diseases : Volume 18
European Journal of Clinical Microbiology & Infectious Diseases : Volume 17
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 12, December 1997
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 11, November 1997
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 10, October 1997
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 9, September 1997
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 8, August 1997
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 7, July 1997
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 6, June 1997
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 5, May 1997
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 4, April 1997
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 3, March 1997
Overview of the etiology of wound infections with particular emphasis on community-acquired illnesses
Central venous catheter-related sepsis in a cohort of 366 hospitalised patients
Novel approach to investigate a source of microbial contamination of central venous catheters
Cefdinir versus amoxicillin/clavulanic acid in the treatment of suppurative acute otitis media in children
Cost-effectiveness of screening blood donors for hepatitis C and non-A, non-B, non-C hepatitis
Evaluation of the E test for fluconazole susceptibility testing ofCandida albicans isolates from oropharyngeal candidiasis
Molecular DNA analysis for differentiation of persistence or relapse from recurrence in treatment failure ofStreptococcus pyogenes pharyngitis
Outbreak ofEscherichia coli O157:H7 infection in a large family
Acute mediastinitis due toRhodococcus equi in a patient with human immunodeficiency virus infection
Vertebral osteomyelitis caused by group B streptococci (Streptococcus agalactiae) secondary to urinary tract infection
Pleural and peritoneal leishmaniasis in an AIDS patient
Significance of indeterminate reactivity to human T-Cell lymphotropic virus in Western blot analysis of individuals at risk
Absence ofBurkholderia cepacia from the respiratory tract of non-cystic fibrosis patients
Five cases of extraoral infection associated withEikenella corrodens
Intraocular candidiasis in candidemic patients
Announcements
Recent book publications
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 2, February 1997
European Journal of Clinical Microbiology & Infectious Diseases : Volume 16, Issue 1, January 1997

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Central venous catheter-related sepsis in a cohort of 366 hospitalised patients

Content Provider Springer Nature Link
Author Tacconelli, E. Tumbarello, M. Pittiruti, M. Leone, F. Lucia, M. B. Cauda, R. Ortona, L.
Copyright Year 1997
Abstract Five hundred two central venous catheters inserted in 366 patients were evaluated prospectively over a one-year period to determine the frequency and risk factors associated with catheter-related sepsis. For study purposes, in cases in which catheter infection was suspected but the initial blood cultures were negative, the catheters were replaced by guidewire technique; otherwise, the catheters were routinely changed after 21 days by guidewire technique. A catheter-related infection was suspected in 190 cases (190/502, 38%). A diagnosis of catheter-related sepsis was established in 50 patients, which represents 10% of the total number of lines (502). Over a total of 6428 days of catheter use, the infection rate was 0.8 cases of sepsis per 100 catheter-days.Staphylococcus epidermidis, Staphylococcus aureus, andCandida spp. were the most frequently isolated aetiological agents of sepsis. On univariate analysis, six variables affecting the rate of catheter-related sepsis were identified: neutropenia for more than eight days (p<0.001); AIDS (p<0.001); haematological malignancy (p<0.001); administration of total parenteral nutrition (p=0.001); duration of site use (p=0.04); and high APACHE II score (p=0.04). The logistic regression analysis revealed that AIDS and haematological malignancies were independent risk factors of catheter-related sepsis. Catheter replacement over a guidewire was no more likely to be associated with sepsis than was percutaneous catheter insertion. In conclusion, although the incidence of established catheter infection is much lower than the incidence of suspected infection, in most cases of suspected infection it is wise to change the catheter with the guidewire technique and wait for culture of the tip, rather than to remove the catheter immediately. Such a policy may help reduce the number of unnecessary catheter removals.
Starting Page 203
Ending Page 209
Page Count 7
File Format PDF
ISSN 09349723
Journal European Journal of Clinical Microbiology & Infectious Diseases
Volume Number 16
Issue Number 3
e-ISSN 14354373
Language English
Publisher Springer-Verlag
Publisher Date 1997-01-01
Publisher Place Berlin, Heidelberg
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Medical Microbiology Internal Medicine
Content Type Text
Resource Type Article
Subject Infectious Diseases Microbiology (medical)
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