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| Content Provider | Springer Nature Link |
|---|---|
| Author | Bermudes, H. Arpin, C. Jude, F. El Harrif, Z. Bébéar, C. Quentin, C. |
| Copyright Year | 1997 |
| Abstract | Between June 1992 and June 1993, 128 extended-spectrum β-lactamase-producing enterobacteria (123Klebsiella pneumoniae, 3Escherichia coli, 1Enterobacter aerogenes, and 1Citrobacter diversus) were collected in a French university hospital. These isolates were recovered mainly from patients hospitalized in intensive care and neurosurgery units. The 128 strains were divided into 14 antibiotypes (ATBs; ATB1 to ATB14); 102 of 103 nonredundant isolates were shown to produce an SHV-4-related extendedspectrum β-lactamase (pl 7.8, hybridization with abla SHV probe); the remaining strain (Kp 2108) produced a TEM-3-related extended-spectrum β-lactamase (pI 6.3, hybridization with abla TEM probe). For representative isolates, five plasmid profiles (PI to PII4), eight ribotypes (E1 to E8), and seven arbitrarily primed polymerase chain reaction profiles (A1 to A7) were obtained. The results suggest the spread of an epidemic strain ofKlebsiella pneumoniae (E1, A1, PI, various ATBs) from an intensive care unit throughout the hospital. Another epidemic strain (E2, A2, PI, ATB4) was confined to the neurosurgery unit. Other extended-spectrum β-lactamase-producingKlebsiella pneumoniae of ribotypes distinct from E1 or E2 might result from the spread of an epidemic plasmid, such as reported for isolates of other enterobacterial species. Conversely, they might represent imported cases, such as the strain Kp 2108, which produced a TEM-3-related β-lactamase. |
| Starting Page | 523 |
| Ending Page | 529 |
| Page Count | 7 |
| File Format | |
| ISSN | 09349723 |
| Journal | European Journal of Clinical Microbiology & Infectious Diseases |
| Volume Number | 16 |
| Issue Number | 7 |
| e-ISSN | 14354373 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 1997-01-01 |
| Publisher Place | Berlin, Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Medical Microbiology Internal Medicine |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Microbiology (medical) |
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