NDLI: Screening of antioxidant and antitumor activities of major ingredients from defatted Camellia oleifera seeds

Content Provider	Springer Nature Link
Author	Li, Tingting Zhang, Hui Wu, Cai e
Copyright Year	2014
Abstract	Three major ingredients (saponin, protein, and polysaccharide) were obtained from defatted Camellia oleifera Abel seeds by sequential extraction. A series of experiments were conducted to compare the antioxidant and antitumor activities of these three major ingredients. The antioxidant activities of these ingredients were evaluated by reducing power, hydroxyl, superoxide anion, and DPPH radical scavenging assays. All antioxidant tests showed that the protein had the highest antioxidant activity among the three samples, and the antioxidant effects of protein increased in a dose-dependent manner. In vitro, the antitumor activities of the three major ingredients against Hep G2 cells at different concentrations were examined by MTT assay. The polysaccharide exhibited the highest potency against Hep G2 cells, with an IC50 value of 5.826 μg/mL, followed by saponin (26.754 μg/mL). These findings suggest that the protein and polysaccharide from defatted C. oleifera seeds exhibit significant antioxidant and antitumor activities, respectively, which deserve further research.
Starting Page	873
Ending Page	880
Page Count	8
File Format	PDF
ISSN	12267708
Journal	Food Science and Biotechnology
Volume Number	23
Issue Number	3
e-ISSN	20926456
Language	English
Publisher	The Korean Society of Food Science and Technology
Publisher Date	2014-06-30
Publisher Place	Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Camellia oleifera Abel antioxidan antitumor protein polysaccharide Food Science Nutrition
Content Type	Text
Resource Type	Article
Subject	Applied Microbiology and Biotechnology Food Science Biotechnology

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