NDLI: APOE and APOC1 genetic polymorphisms in age-associated memory impairment

Content Provider	Springer Nature Link
Author	Bartrés Faz, D. Clemente, I.C. Junqué, C. Valveny, N. López Alomar, A. Sánchez Aldeguer, J. López Guillén, A. Moral, P.
Copyright Year	2001
Abstract	We studied the distribution of two genetic polymorphisms (APOE and APOC1) in a sample of 100 subjects fulfilling the NIMH criteria for age-associated memory impairment (AAMI) and 124 controls. We found significant associations both for APOE and APOC1 loci and their combinations with the AAMI condition. The findings in our sample suggest that memory-impaired subjects as described by the NIMH may be genetically differentiated from normally aging subjects in relation to these two polymorphisms and indicate the interest of considering variations in the APOC1 gene for further studies in cognitive aging.
Starting Page	215
Ending Page	219
Page Count	5
File Format	PDF
ISSN	13646745
Journal	Neurogenetics
Volume Number	3
Issue Number	4
Language	English
Publisher	Springer-Verlag
Publisher Date	2001-09-07
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Content Type	Text
Resource Type	Article
Subject	Genetics Cellular and Molecular Neuroscience Genetics (clinical)

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APOE and APOC1 genetic polymorphisms in age-associated memory impairment