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| Content Provider | Springer Nature Link |
|---|---|
| Author | Katara, Pramod Grover, Atul Sharma, Vinay |
| Copyright Year | 2011 |
| Abstract | Phylogenetic footprinting is a method for the discovery of regulatory elements in a set of homologous regulatory regions, usually collected from multiple species. It does so by identifying the best conserved motifs in those homologous regions. There are two popular sets of methods—alignment-based and motif-based, which are generally employed for phylogenetic methods. However, serious efforts have lacked to develop a tool exclusively for phylogenetic footprinting, based on either of these methods. Nevertheless, a number of software and tools exist that can be applied for prediction of phylogenetic footprinting with variable degree of success. The output from these tools may get affected by a number of factors associated with current state of knowledge, techniques and other resources available. We here present a critical apprehension of various phylogenetic approaches with reference to prokaryotes outlining the available resources and also discussing various factors affecting footprinting in order to make a clear idea about the proper use of this approach on prokaryotes. |
| Starting Page | 901 |
| Ending Page | 907 |
| Page Count | 7 |
| File Format | |
| ISSN | 0033183X |
| Journal | Protoplasma |
| Volume Number | 249 |
| Issue Number | 4 |
| e-ISSN | 16156102 |
| Language | English |
| Publisher | Springer Vienna |
| Publisher Date | 2011-11-24 |
| Publisher Place | Vienna |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Footprinting Binding sites Regulatory elements Motif Plant Sciences Zoology Cell Biology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Plant Science Medicine |
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