NDLI: Hepatitis E virus infection in patients on dialysis and in solid organ transplant recipients in Argentina: exploring associated risk factors

Content Provider	Springer Nature Link
Author	Pisa, María Belén Balderramo, Domingo Wassaf, Maribel Martínez Lotto, Martín Carli, Yanina Ré, Viviana Elizabeth Debes, José D.
Copyright Year	2016
Abstract	Infection with hepatitis E virus (HEV) leads to acute hepatitis infection in immunocompetent hosts. HEV genotype 3 can present with high frequency and lead to chronic infection in individuals with a compromised immune system. The risk factors related to increased seroprevalence or chronicity in this population are not entirely understood. Moreover, most studies addressing risk factors for HEV in non-endemic areas come from developed areas such as North America and Europe. In this study we evaluated seroprevalence, chronicity and risk factors for HEV in 120 transplant recipients and 88 patients on dialysis in Argentina. We found a significantly higher seroprevalence of HEV IgG in those undergoing dialysis compared with healthy controls (10.2% and 4.3% respectively, p = 0.03). No difference in HEV seroprevalence was observed between healthy controls and transplant recipients (5.8%). We found no association between previously identified risk factors for HEV, such as pork consumption or use of tacrolimus, and HEV seroprevalence. In univariate and multivariate analyses, consumption of fish was associated with higher seroprevalence of HEV (OR = 9.33; 95% CI: 2.07–42.2; p = 0.04). None of the samples showed HEV RNA amplification, indicating that chronicity does not seem to be an issue in these cohorts. Our results show increased seroprevalence of HEV in individuals undergoing dialysis but not in transplant recipients. We also found that fish consumption can be a potential risk factor for acquiring HEV.
Starting Page	787
Ending Page	792
Page Count	6
File Format	PDF
ISSN	03048608
Journal	Archives of Virology
Volume Number	162
Issue Number	3
e-ISSN	14328798
Language	English
Publisher	Springer Vienna
Publisher Date	2016-11-25
Publisher Place	Vienna
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Virology Medical Microbiology Infectious Diseases
Content Type	Text
Resource Type	Article
Subject	Virology Medicine

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Hepatitis E Virus Infection without Reactivation in Solid-Organ Transplant Recipients, France

Mucosal Candida infection and colonisation as well as associated risk factors in solid organ transplant recipients

Hepatitis E Virus Infection among Solid Organ Transplant Recipients, the Netherlands

Hepatitis E Virus Infection without Reactivation in Solid-Organ Transplant Recipients, France

Nontuberculous mycobacteria infection in solid organ transplant recipients

Statins are associated with improved outcomes of bloodstream infection in solid-organ transplant recipients

Increased risk of hepatitis E virus infection in schizophrenia

Hepatitis E Virus Infection Among Solid Organ Transplant Recipients at a North American Transplant Center

Risk Factors Associated with Adenovirus Infection in Solid Organ Transplant Recipients

Hepatitis E virus infection in patients on dialysis and in solid organ transplant recipients in Argentina: exploring associated risk factors

Similar Documents

Hepatitis E Virus Infection without Reactivation in Solid-Organ Transplant Recipients, France

Mucosal Candida infection and colonisation as well as associated risk factors in solid organ transplant recipients

Hepatitis E Virus Infection among Solid Organ Transplant Recipients, the Netherlands

Hepatitis E Virus Infection without Reactivation in Solid-Organ Transplant Recipients, France

Nontuberculous mycobacteria infection in solid organ transplant recipients

Statins are associated with improved outcomes of bloodstream infection in solid-organ transplant recipients

Increased risk of hepatitis E virus infection in schizophrenia

Hepatitis E Virus Infection Among Solid Organ Transplant Recipients at a North American Transplant Center

Risk Factors Associated with Adenovirus Infection in Solid Organ Transplant Recipients

Hepatitis E virus infection in patients on dialysis and in solid organ transplant recipients in Argentina: exploring associated risk factors