NDLI: Development of a biological detection platform utilizing a modular microfluidic stack

Content Provider	Springer Nature Link
Author	Frische, Niklas Datta, Proyag Goettert, Jost
Copyright Year	2010
Abstract	The goal of this project is to build a miniaturized, user-friendly cytometry setup (Datta et al. in Microfluidic platform for education and research. COMS, Baton Rouge, 2008; Frische et al. in Development of an miniaturized flow cytometry setup for visual cell inspection and sorting. Baton Rouge, Project Report, 2008) by combining a customized, microfluidic device with visual microscope inspection to detect and extract specific cells from a continuous sample flow. We developed a cytological tool, based on the Coulter particle counter principle, using a microelectrode array patterned on a borosilicate glass chip as electrical detection set-up which is fully embedded into a polymeric multi-layer microfluidic stack. The detection takes place between pairs of coplanar Cr/Au microelectrodes by sensing an impedance change caused by particles continuously carried within a microfluidic channel across the detection area under laminar flow conditions. A wide frequency range available for counting provides information on cell size, membrane capacitance, cytoplasm conductivity and is potentially of interest for in-depth cell diagnostic e.g. to detect damaged or cancerous cells and select them for extraction and further in-depth analysis.
Starting Page	1553
Ending Page	1561
Page Count	9
File Format	PDF
ISSN	09467076
Journal	Microsystem Technologies
Volume Number	16
Issue Number	8-9
e-ISSN	14321858
Language	English
Publisher	Springer-Verlag
Publisher Date	2010-03-09
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Electronics and Microelectronics, Instrumentation Mechanical Engineering Nanotechnology
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Condensed Matter Physics Electronic, Optical and Magnetic Materials Electrical and Electronic Engineering Hardware and Architecture

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Enhanced efficiency of sorting sperm motility utilizing a microfluidic chip

Integration of impedance spectroscopy sensors in a digital microfluidic platform

Fabrication of microfluidic channel utilizing silicone rubber with vacuum casting

Utilization of nanoparticles in microfluidic systems for optical detection

Triplex-pumping CD-like microfluidic platform with parabolic microchannels

A microvalve for hybrid microfluidic systems

Modeling of capacitively coupled contactless conductivity detection on microfluidic chips

Decanting and mixing of supernatant human blood plasma on centrifugal microfluidic platform

A microfluidic device for generation of chemical gradients

Development of a biological detection platform utilizing a modular microfluidic stack

Similar Documents

Enhanced efficiency of sorting sperm motility utilizing a microfluidic chip

Integration of impedance spectroscopy sensors in a digital microfluidic platform

Fabrication of microfluidic channel utilizing silicone rubber with vacuum casting

Utilization of nanoparticles in microfluidic systems for optical detection

Triplex-pumping CD-like microfluidic platform with parabolic microchannels

A microvalve for hybrid microfluidic systems

Modeling of capacitively coupled contactless conductivity detection on microfluidic chips

Decanting and mixing of supernatant human blood plasma on centrifugal microfluidic platform

A microfluidic device for generation of chemical gradients

Development of a biological detection platform utilizing a modular microfluidic stack