NDLI: Ambient temperature and activation of implantable cardioverter defibrillators

Content Provider	Springer Nature Link
Author	McGuinn, L. Hajat, S. Wilkinson, P. Armstrong, B. Anderson, H. R. Monk, V. Harrison, R.
Copyright Year	2012
Abstract	The degree to which weather influences the occurrence of serious cardiac arrhythmias is not fully understood. To investigate, we studied the timing of activation of implanted cardiac defibrillators (ICDs) in relation to daily outdoor temperatures using a fixed stratum case-crossover approach. All patients attending ICD clinics in London between 1995 and 2003 were recruited onto the study. Temperature exposure for each ICD patient was determined by linking each patient’s postcode of residence to their nearest temperature monitoring station in London and the South of England. There were 5,038 activations during the study period. Graphical inspection of ICD activation against temperature suggested increased risk at lower but not higher temperatures. For every 1 °C decrease in ambient temperature, risk of ventricular arrhythmias up to 7 days later increased by 1.2 % (95 % CI −0.6 %, 2.9 %). In threshold models, risk of ventricular arrhythmias increased by 11.2 % (0.5 %, 23.1 %) for every 1° decrease in temperature below 2 °C. Patients over the age of 65 exhibited the highest risk. This large study suggests an inverse relationship between ambient outdoor temperature and risk of ventricular arrhythmias. The highest risk was found for patients over the age of 65. This provides evidence about a mechanism for some cases of low-temperature cardiac death, and suggests a possible strategy for reducing risk among selected cardiac patients by encouraging behaviour modification to minimise cold exposure.
Starting Page	655
Ending Page	662
Page Count	8
File Format	PDF
ISSN	00207128
Journal	International Journal of Biometeorology
Volume Number	57
Issue Number	5
e-ISSN	14321254
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2012-09-20
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Arrhythmia Environment Epidemiology Risk factor Weather Biophysics and Biological Physics Meteorology Animal Physiology Plant Physiology Environmental Health
Content Type	Text
Resource Type	Article
Subject	Ecology Health, Toxicology and Mutagenesis Atmospheric Science

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