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Bioprocess kinetics in a horizontal rotating tubular bioreactor

Content Provider	Springer Nature Link
Author	Ivančić, M. Šantek, B. vak, S. Horvat, P. Marić, V.
Copyright Year	2004
Abstract	A horizontal rotating tubular bioreactor (HRTB) is a plug flow bioreactor whose interior is provided with O-ring-shaped partition walls that serve as carriers for microbial biomass. During this investigation, microbial biomass was grown in suspension and on the bioreactor inner surface as a microbial biofilm with average mass that was considerably higher than suspended biomass. The dynamics of bioprocess in HRTB was studied by different combinations of process parameters (bioreactor rotation speed and mean residence time) and it was monitored by withdrawing the samples from five positions along the bioreactor. During this investigation it was also observed that mean residence time had a more pronounced effect on the bioprocess dynamics than bioreactor rotation speed. For the description of bioprocess kinetics in HRTB an unstructured kinetic model was established that defines biomass growth, product formations and substrate consumption rate by using a modified Monod (Levenspiel) model. This kinetic model defines changes in suspension and in microbial biofilm, and it shows relatively good agreement with experimental data.
Starting Page	169
Ending Page	175
Page Count	7
File Format	PDF
ISSN	16157591
Journal	Bioprocess Engineering
Volume Number	26
Issue Number	3
e-ISSN	16157605
Language	English
Publisher	Springer-Verlag
Publisher Date	2004-02-19
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Horizontal rotating tubular bioreactor (HRTB) Mixed microbial culture Bioprocess kinetics Unstructured kinetic model
Content Type	Text
Resource Type	Article
Subject	Medicine Bioengineering Biotechnology

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