Please wait, while we are loading the content...
Please wait, while we are loading the content...
| Content Provider | Springer Nature Link |
|---|---|
| Author | Zarnescu, Otilia |
| Copyright Year | 2007 |
| Abstract | The acetylation of core histones has been correlated with the deposition of free histones onto newly replicated DNA, transcriptional activity and the displacement of histones by protamines during spermiogenesis. The aim of the present study was to investigate the immunohistochemical distribution of hyperacetylated H4 during spermatogenesis in Polyodon spathula and to correlate these findings with the pattern of chromatin condensation in spermatids. In immature testis, the Sertoli cells showed more intense immunoreactivity for highly acetylated H4 than that of most primary spermatogonia. The testis of paddlefish at the beginning of spermatogenesis possessed early secondary spermatogonia and late secondary spermatogonia/preleptotene primary spermatocyte with intense nuclear immunoreactivity for highly acetylated H4. In seminiferous tubules in which secondary spermatogonia nuclei were intensely immunostained, Sertoli cell nuclei were unstained. Testes in late spermatogenesis contained tubules in which the immunohistochemical reaction for highly acetylated H4 was positive in the nuclei of preleptotene primary spermatocytes and secondary spermatocytes and in spermatids at the beginning of the elongation process. No immunostaining was found in round spermatids and spermatozoa. During the resting stage, immunostaining was confined to the nuclei of spermatogonia and the cells from the interstitial tissue. Transmission electron microscopy revealed that early spermatids had a round nucleus with filaments of fine chromatin that were dispersed or condensed in clumps. In later stages of maturation, the spermatids had slightly oval nuclei and homogeneous granular chromatin. The chromatin of advanced spermatids was organized into thick fibres. At the end of spermiogenesis, spermatozoan nuclei consisted of homogeneous highly compacted chromatin. |
| Starting Page | 401 |
| Ending Page | 410 |
| Page Count | 10 |
| File Format | |
| ISSN | 0302766X |
| Journal | Cell and Tissue Research |
| Volume Number | 328 |
| Issue Number | 2 |
| e-ISSN | 14320878 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2007-01-25 |
| Publisher Place | Berlin, Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Testis Hyperacetylated histone H4 Spermatogenesis Spermatid ultrastructure Paddlefish, Polyodon spathula (Acipenseriformes, Polyodontidae) Molecular Medicine Proteomics Human Genetics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Histology Pathology and Forensic Medicine |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|