NDLI: Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations

Please wait, while we are loading the content...

Extensively high load of internal tumors determined by whole body MRI scanning in a patient with neurofibromatosis type 1 and a non-LCR-mediated 2-Mb deletion in 17q11.2

FISH analysis of hematological neoplasias with 1p36 rearrangements allows the definition of a cluster of 2.5 Mb included in the minimal region deleted in 1p36 deletion syndrome

Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome

BRCA1 variants in a family study of African-American and Latina women

Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations

Rapid genotyping for most common TGFBI mutations with real-time polymerase chain reaction

Matrix Gla protein and osteopontin genetic associations with coronary artery calcification and bone density: the CARDIA study

On the evolutionary mutation rate at Y-chromosome STRs: comments on paper by Di Giacomo et al. (2004)

Human Gene Mutations

Human Genetics : Volume 116, Issue 5, April 2005

Human Genetics : Volume 116, Issue 4, March 2005

Human Genetics : Volume 116, Issue 3, February 2005

Human Genetics : Volume 116, Issue 1-2, January 2005

Human Genetics : Volume 115

Human Genetics : Volume 114

Human Genetics : Volume 113

Human Genetics : Volume 112

Human Genetics : Volume 111

Human Genetics : Volume 110

Human Genetics : Volume 109

Human Genetics : Volume 108

Human Genetics : Volume 107

Human Genetics : Volume 106

Human Genetics : Volume 105

Human Genetics : Volume 104

Human Genetics : Volume 103

Human Genetics : Volume 102

Human Genetics : Volume 101

Human Genetics : Volume 100

Human Genetics : Volume 99

Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations

Content Provider	Springer Nature Link
Author	Thangaraj, Kumarasamy Sridhar, Vempati Kivisild, Toomas Reddy, Alla G. Chaubey, Gyaneshwer Singh, Vijay Kumar Kaur, Suminder Agarawal, Pooja Rai, Amit Gupta, Jalaj Mallick, Chandana Basu Kumar, Niraj Velavan, Thrimulaisamy P. Suganthan, Rajanbabu Udaykumar, Divi Kumar, Rashmi Mishra, Rachana Khan, Arif Annapurna, Chitikineni Singh, Lalji
Copyright Year	2005
Abstract	Length variation in the human mtDNA intergenic region between the cytochrome oxidase II (COII) and tRNA lysine (tRNAlys) genes has been widely studied in world populations. Specifically, Austronesian populations of the Pacific and Austro-Asiatic populations of southeast Asia most frequently carry the 9-bp deletion in that region implying their shared common ancestry in haplogroup B. Furthermore, multiple independent origins of the 9-bp deletion at the background of other mtDNA haplogroups has been shown in populations of Africa, Europe, Australia, and India. We have analyzed 3293 Indian individuals belonging to 58 populations, representing different caste, tribal, and religious groups, for the length variation in the 9-bp motif. The 9-bp deletion (one copy) and insertion (three copies) alleles were observed in 2.51% (2.15% deletion and 0.36% insertion) of the individuals. The maximum frequency of the deletion (45.8%) was observed in the Nicobarese in association with the haplogroup B5a D-loop motif that is common throughout southeast Asia. The low polymorphism in the D-loop sequence of the Nicobarese B5a samples suggests their recent origin and a founder effect, probably involving migration from southeast Asia. Interestingly, none of the 302 (except one Munda sample, which has 9-bp insertion) from Mundari-speaking Austro-Asiatic populations from the Indian mainland showed the length polymorphism of the 9-bp motif, pointing either to their independent origin from the Mon-Khmeric-speaking Nicobarese or to an extensive admixture with neighboring Indo-European-speaking populations. Consistent with previous reports, the Indo-European and Dravidic populations of India showed low frequency of the 9-bp deletion/insertion. More than 18 independent origins of the deletion or insertion mutation could be inferred in the phylogenetic analysis of the D-loop sequences.
Starting Page	507
Ending Page	517
Page Count	11
File Format	PDF
ISSN	03406717
Journal	Human Genetics
Volume Number	116
Issue Number	6
e-ISSN	14321203
Language	English
Publisher	Springer-Verlag
Publisher Date	2005-03-17
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Content Type	Text
Resource Type	Article
Subject	Genetics Genetics (clinical)

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations

Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations

Status of austro-asiatic tribes in the peopling of India:an exploratory study based on available palaeontological,ethno-historic,linguistic and biological data

Microsatellite DYS385 Polymorphism among the Tai and Mon-Khmer Speaking Populations of Northern Thailand

Evolutionary history of the mtDNA 9-bp deletion in Chinese populations and its relevance to the peopling of east and southeast Asia

Status of Austro-Asiatic groups in the peopling of India: An exploratory study based on the available prehistoric, linguistic and biological evidences

Groups and their affinity to the neighbouring.

Insertion–Deletion Polymorphism of Mitochondrial DNA Region V in Kazakh Populations from Different Regions of Kazakhstan

About the "Asian"-specific 9-bp deletion of mtDNA....

Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations

Similar Documents

Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations

Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations

Status of austro-asiatic tribes in the peopling of India:an exploratory study based on available palaeontological,ethno-historic,linguistic and biological data

Microsatellite DYS385 Polymorphism among the Tai and Mon-Khmer Speaking Populations of Northern Thailand

Evolutionary history of the mtDNA 9-bp deletion in Chinese populations and its relevance to the peopling of east and southeast Asia

Status of Austro-Asiatic groups in the peopling of India: An exploratory study based on the available prehistoric, linguistic and biological evidences

Groups and their affinity to the neighbouring.

Insertion–Deletion Polymorphism of Mitochondrial DNA Region V in Kazakh Populations from Different Regions of Kazakhstan

About the "Asian"-specific 9-bp deletion of mtDNA....

Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations