NDLI: Comparative Efficacy of an Imidacloprid/Flumethrin Collar (Seresto®) and an Oral Fluralaner Chewable Tablet (Bravecto®) against Tick (Dermacentor variabilis and Amblyomma americanum) Infestations on Dogs: a Randomised Controlled Trial

Content Provider	Springer Nature Link
Author	Ohmes, Cameon M. Hostetler, Joe Davis, Wendell L. Settje, Terry McMinn, Amy Everett, William R.
Copyright Year	2015
Abstract	This controlled laboratory study demonstrated the residual speed of efficacy of an imidacloprid/flumethrin collar (Seresto®, Bayer) for the control of ticks (Dermacentor variabilis, Amblyomma americanum) at 6 and 12 hours post-infestation on dogs when compared to oral fluralaner (Bravecto®, Merck). Dogs were randomised by pre-treatment tick counts: Group 1) imidacloprid 10 % (w/w)/flumethrin 4.5 % (w/w) collar, 2) fluralaner (dosage 25.1 – 49.4 mg/kg), and 3) non-treated controls. Ticks (50/species/dog) were infested on days 3, 14, 21, 28, 42, and 56 followed by 50 D. variabilis on days 70 and 84. Live and dead attached ticks were counted 6 and 12 hours later. Efficacy against both species at 6 and 12 hours for Group 1 was 94 – 100 %. Efficacy for Group 2 against both species at 6 hours was 4 – 69 %; efficacy at 12 hours was 8 – 100 %. Live (attached and non-attached) tick counts at 6 hours in Group 1 were significantly lower (p ≤ 0.05) than counts in Group 2 and 3 on all days. At 12 hours, live counts were significantly lower (p ≤ 0.05) in Group 1 than Group 2 for D. variabilis from days 56 – 84 and for A. americanum from days 28 – 56. There were significantly fewer (p ≤ 0.05) total ticks (total live and dead attached) on dogs in Group 1 compared to Group 2 and 3 at all time points. This study demonstrated that an imidacloprid/flumethrin collar was highly efficacious (94 – 100 %) at repelling and killing ticks on dogs at 6 and 12 hours post-infestation and was more efficacious than fluralaner as early as 6 hours post-infestation on all challenge days.
Starting Page	95
Ending Page	108
Page Count	14
File Format	PDF
ISSN	09320113
Journal	Parasitology Research
Volume Number	114
Issue Number	1
e-ISSN	14321955
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2015-07-09
Publisher Place	Berlin/Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Medical Microbiology Microbiology Immunology
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Veterinary Parasitology Insect Science

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Comparative Efficacy of an Imidacloprid/Flumethrin Collar (Seresto®) and an Oral Afoxolaner Chewable (NexGard®) against Tick (Dermacentor variabilis and Amblyomma americanum) Infestations on Dogs: a Randomised Controlled Trial

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Efficacy of fluralaner chewable tablets (Bravecto®) against Asian longhorned tick (Haemaphysalis longicornis) infestations of dogs

Efficacy of an Imidacloprid 10 % / Flumethrin 4.5 % Collar (Seresto®, Bayer) for Preventing the Transmission of Cytauxzoon felis to Domestic Cats by Amblyomma americanum

Long-Term Efficacy of an Imidacloprid 10 % / Flumethrin 4.5 % Polymer Matrix Collar (Seresto®, Bayer) against the Australian Paralysis Tick (Ixodes holocyclus) in Dogs

Repellency Effect of an Imidacloprid / Flumethrin (Seresto®) Controlled Release Polymer Matrix Collar against the Australian Paralysis Tick (Ixodes holocyclus) in Dogs

Extermination Speed of an Imidacloprid and Flumethrin Polymer Matrix Collar against Larvae, Nymphs and Adults of Haemaphysalis longicornis.

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Comparative Efficacy of an Imidacloprid/Flumethrin Collar (Seresto®) and an Oral Fluralaner Chewable Tablet (Bravecto®) against Tick (Dermacentor variabilis and Amblyomma americanum) Infestations on Dogs: a Randomised Controlled Trial

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